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脓毒症休克患者对促肾上腺皮质激素的皮质醇反应与生存情况

Cortisol response to corticotropin and survival in septic shock.

作者信息

Rothwell P M, Udwadia Z F, Lawler P G

机构信息

Intensive Therapy Unit, South Cleveland Hospital, Middlesbrough, UK.

出版信息

Lancet. 1991 Mar 9;337(8741):582-3. doi: 10.1016/0140-6736(91)91641-7.

DOI:10.1016/0140-6736(91)91641-7
PMID:1671944
Abstract

Corticotropin stimulation tests were used to assess adrenocortical function in 32 patients with septic shock. 13 patients had a poor cortisol response (rise less than 250 nmol/l) to corticotropin, all of whom died. However, there were only 6 deaths among the 19 patients with adequate responses (p less than 0.001). These results suggest that some patients with septic shock may have relative adrenocortical insufficiency.

摘要

促肾上腺皮质激素刺激试验用于评估32例感染性休克患者的肾上腺皮质功能。13例患者对促肾上腺皮质激素的皮质醇反应较差(升高幅度小于250 nmol/l),所有这些患者均死亡。然而,在19例反应良好的患者中仅有6例死亡(p<0.001)。这些结果表明,一些感染性休克患者可能存在相对性肾上腺皮质功能不全。

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Cortisol response to corticotropin and survival in septic shock.脓毒症休克患者对促肾上腺皮质激素的皮质醇反应与生存情况
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Cortisol response to corticotropin and survival in septic shock.脓毒性休克中皮质醇对促肾上腺皮质激素的反应及生存情况
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