Rosso Edoardo, Bachellier Philippe, Oussoultzoglou Elie, Scurtu Radu, Meyer Nicolas, Nakano Hiroshi, Verasay Guillermo, Jaeck Daniel
Centre de Chirurgie Viscérale et de Transplantation, Hautepierre Hospital, Hôpitaux Universitaires de Strasbourg, Louis-Pasteur University, Avenue Moliere, 67200, Strasbourg, France.
Am J Surg. 2006 Jun;191(6):726-32; discussion 733-4. doi: 10.1016/j.amjsurg.2005.09.012.
Postoperative morbidity after pancreaticoduodenectomy has been associated mainly with the development of pancreatic fistula. However, postoperative complications unrelated to pancreatic fistula cannot be disregarded after pancreaticoduodenectomy. The aim of the present study was to investigate the postoperative morbidity in a large series of pancreaticoduodenectomies with pancreaticogastrostomies without pancreatic fistula.
The present study analyzed the data from 194 consecutive patients undergoing a pancreaticoduodenectomy with a pancreaticogastrostomy between July 1997 and June 2003 in whom no postoperative pancreatic fistula occurred.
The overall rate of postoperative morbidity was 33.5%. Specific and general complications occurred in 16% and 17.5% of the patients, respectively. An American Society of Anesthesiologists (ASA) score of 3 and blood transfusion were the only independent factors associated with postoperative morbidity.
Our study found that the overall morbidity after a pancreaticoduodenectomy with a pancreaticogastrostomy still remains high even in the absence of pancreatic fistula and is associated with the preoperative medical condition (ASA score) of the patients and with blood transfusion.
胰十二指肠切除术后的发病情况主要与胰瘘的发生有关。然而，胰十二指肠切除术后与胰瘘无关的术后并发症也不容忽视。本研究的目的是调查一系列行胰胃吻合术且无胰瘘的胰十二指肠切除术患者的术后发病情况。
本研究分析了1997年7月至2003年6月期间连续194例行胰十二指肠切除并胰胃吻合术且术后未发生胰瘘患者的数据。
术后总体发病率为33.5%。特异性和一般性并发症分别发生在16%和17.5%的患者中。美国麻醉医师协会（ASA）评分为3分和输血是与术后发病相关的仅有的独立因素。
我们的研究发现，即使没有胰瘘，行胰胃吻合术的胰十二指肠切除术后总体发病率仍然很高，并且与患者术前的健康状况（ASA评分）和输血有关。
