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神经性厌食症和贪食症的诊断亚型之间,焦虑症和抑郁症的发病率是否存在差异?

Does the frequency of anxiety and depressive disorders differ between diagnostic subtypes of anorexia nervosa and bulimia?

作者信息

Godart Nathalie, Berthoz Sylvie, Rein Zoé, Perdereau Fabienne, Lang François, Venisse Jean-Luc, Halfon Olivier, Bizouard Pierre, Loas Gwénolé, Corcos Maurice, Jeammet Philippe, Flament Martine, Curt Florence

机构信息

Department of Psychiatry, Université Paris-Descartes, Faculté de médecine, Site Institut Mutualiste Montsouris (IMM), Paris, France.

出版信息

Int J Eat Disord. 2006 Dec;39(8):772-8. doi: 10.1002/eat.20274.

Abstract

OBJECTIVE

The objective of the present work is to determine whether the prevalence of depressive and anxiety disorders varies in subgroups of eating disorders (ED) according to age, ED duration, mode of care provision, and body mass index (BMI).

METHOD

Using the Mini International Neuropsychiatric Interview (MINI), the frequency of anxiety and depressive disorders was evaluated in 271 ED participants. Their prevalence was compared in subgroups of anorexics (AN-R and AN-BN) and bulimics (BN), both before and after controlling for potential confounding variables.

RESULTS

Current or lifetime comorbidity of anxiety and depressive disorders did not differ between AN-R and AN-BN groups. Social phobia, panic disorders, and obsessive-compulsive disorder (OCD) were significantly more frequent in AN-BN and AN-R groups. Panic disorder was more frequent in the BN group.

CONCLUSION

Several confounding factors, in particular those identified in the present study, may explain previous conflicting results on the frequency of anxiety and depressive disorders in ED. Nevertheless, the study confirmed that OCD is more frequent in AN, even after controlling for confounding factors.

摘要

目的

本研究的目的是确定抑郁和焦虑障碍的患病率在饮食失调(ED)亚组中是否因年龄、ED病程、护理提供方式和体重指数(BMI)而有所不同。

方法

使用迷你国际神经精神访谈(MINI),对271名ED参与者的焦虑和抑郁障碍频率进行评估。在控制潜在混杂变量之前和之后,比较厌食症患者(AN-R和AN-BN)和贪食症患者(BN)亚组中的患病率。

结果

AN-R组和AN-BN组之间焦虑和抑郁障碍的当前或终生共病情况没有差异。社交恐惧症、惊恐障碍和强迫症(OCD)在AN-BN组和AN-R组中明显更常见。惊恐障碍在BN组中更常见。

结论

几个混杂因素,特别是本研究中确定的那些因素,可能解释了先前关于ED中焦虑和抑郁障碍频率的相互矛盾的结果。然而,该研究证实,即使在控制了混杂因素之后,OCD在AN中也更常见。

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