Godart Nathalie, Flament Martine, Curt Florence, Perdereau Fabienne, Lang François, Venisse Jean-Luc, Halfon Olivier, Bizouard Paul, Loas Gwenele, Corcos Maurice, Jeammet Philippe, Fermanian Jacques
Réseau INSERM Dépendance number 494013.
Ann Med Interne (Paris). 2003 Sep;154(4):209-18.
We designed a controlled study comparing referred women with an eating disorder (ED) to a matched normal control group to answer the following questions: what are the frequencies of anxiety disorders (AD) in anorexia nervosa (AN) and bulimia nervosa (BN), according to DSM-IV criteria? Are AD significantly more frequent among women with an ED than among women from the community?
We assessed frequencies of six specific AD among 271 women with a current diagnosis of AN or BN and 271 controls, using the Mini International Neuropsychiatric Interview (MINI), French DSM-IV version.
Seventy-one percent of both the AN and the BN subjects had a lifetime comorbidity with at least one AD, significantly more (p<0.001) than the percentage of controls with an AD. Prevalence was significantly higher in the ED groups than in controls for most types of AD, and between 41.8% and 53.3% of comorbid cases had an AD preceding the onset of the ED.
Evidence that AD are significantly more frequent in subjects with ED than in the community has important etiological and therapeutic implications.