Shang Xiao-Ya, Li Chong, Zhang Cheng-Zhong, Yang Yong-Chun, Shi Jian-Gong
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Be'iing 100050, China.
Zhongguo Zhong Yao Za Zhi. 2006 Mar;31(6):468-71.
To study the chemical constituents of a Tibetan medicine Meconopsis quintuplinervia.
Column chromatographic techniques were applied to isolate constituents. A combination of IR, MS and NMR spectroscopy was used to identify structures of constituents.
Twelve compounds were isolated from the ethanolic extract and their structures were elucidated as quercetin 3-O-beta-D-glucopyranoside (I), quercetin 3-O-beta-D-galactopyranosyl-(1-->6)-glucopyranoside (II), kaempferol 3-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (III), isorhamnetin 3-0-beta-D-galactopyranosyl-(1-->6)-beta-D-glucopyranoside (IV), caffeic acid (V), protocatechuic acid (VI), p-hydroxycinnamic (VII), 2-(3,4-dihydroxyphenyl )-ethyl-O-beta-D-glucopyranoside (VIII), p-hydroxybenzoyl-beta-D-glucopyranoside (IX), 4-O-beta-D-glucopyranosyl-(Z)-p-coumaric acid (X), 5, 7-dihydroxy-4H-4-chromenone (XI), daucosterol (XII).
Ten compounds were isolated from this genus for the first time except for XI and XII.
研究藏药五脉绿绒蒿的化学成分。
采用柱色谱技术分离化合物。运用红外光谱、质谱和核磁共振光谱相结合的方法鉴定化合物结构。
从乙醇提取物中分离得到12个化合物，其结构分别鉴定为槲皮素3 - O - β - D - 吡喃葡萄糖苷（I）、槲皮素3 - O - β - D - 吡喃半乳糖基 -（1→6）- 吡喃葡萄糖苷（II）、山柰酚3 - O - β - D - 吡喃葡萄糖基 -（1→2）- β - D - 吡喃葡萄糖苷（III）、异鼠李素3 - O - β - D - 吡喃半乳糖基 -（1→6）- β - D - 吡喃葡萄糖苷（IV）、咖啡酸（V）、原儿茶酸（VI）、对羟基肉桂酸（VII）、2 -（3,4 - 二羟基苯基）- 乙基 - O - β - D - 吡喃葡萄糖苷（VIII）、对羟基苯甲酰 - β - D - 吡喃葡萄糖苷（IX）、4 - O - β - D - 吡喃葡萄糖基 -（Z）- 对香豆酸（X）、5,7 - 二羟基 - 4H - 4 - 色原酮（XI）、胡萝卜苷（XII）。
除XI和XII外，首次从该属植物中分离得到10个化合物。
