Allen P F, Thomason J M, Jepson N J A, Nohl F, Smith D G, Ellis J
National University of Ireland, Cork, Ireland.
J Dent Res. 2006 Jun;85(6):547-51. doi: 10.1177/154405910608500613.
Evidence from randomized clinical trials of implant-retained overdentures is very limited at the present time. The aim of this study was to compare implant-retained mandibular overdentures and conventional complete dentures in a randomized controlled trial (RCT). Our a priori hypothesis was that implant-retained mandibular overdentures would be significantly better than conventional complete dentures. Edentulous patients (n = 118) were randomly allocated to either an Implant Group (n = 62) or a Denture Group (n = 56). Patients completed the Oral Health Impact Profile (OHIP) and a denture satisfaction scale pre-treatment and three months post-treatment. Upon completion of treatment, both groups reported improvement (p < 0.001, Wilcoxon Ranks Sum test) in oral-health-related quality of life and denture satisfaction. There were no significant post-treatment differences between the groups, but a treatment effect may be masked by application of "intention to treat" analysis. The OHIP change scores were significantly greater for patients receiving implants than for those who refused them.
目前，关于种植体支持覆盖义齿的随机临床试验证据非常有限。本研究的目的是在一项随机对照试验（RCT）中比较种植体支持的下颌覆盖义齿和传统全口义齿。我们的先验假设是种植体支持的下颌覆盖义齿明显优于传统全口义齿。无牙患者（n = 118）被随机分配到种植组（n = 62）或义齿组（n = 56）。患者在治疗前和治疗后三个月完成口腔健康影响量表（OHIP）和义齿满意度量表。治疗结束后，两组患者在与口腔健康相关的生活质量和义齿满意度方面均有改善（p < 0.001，Wilcoxon秩和检验）。两组治疗后无显著差异，但应用“意向性分析”可能掩盖了治疗效果。接受种植治疗的患者的OHIP变化评分显著高于拒绝种植的患者。
