J Gastroenterol Hepatol. 2006 Jun;21(6):1009-15. doi: 10.1111/j.1440-1746.2006.04140.x.
The purpose of the present paper was to investigate the status of Crohn's disease hospitalization in China.
Medical records of hospitalized Crohn's disease came from 22 medical centers across China during 1990-2003 and were retrospectively reviewed. Every incident case was recorded in detail on a regular comprehensive datum form by investigators in person. Clinical manifestations, examinations and therapeutic status were analyzed.
A total of 515 cases of Crohn's disease were found. The ratio of patients with Crohn's disease to total hospitalized patients has increased steadily year by year. Endoscopy was performed in 348 patients (67.57%). Barium meal or enema was performed in 221 patients (42.91%). Histological examination (endoscopical or surgical biopsy) was performed in 340 patients (66.02%). Reasonable treatment strategies were used for 435 patients (84.47%). The evaluation of quality of life for 54/303 patients (17.82%) was poor.
This retrospective, hospital-based study shows that the number of patients with Crohn's disease in China has steadily increased over a period of 14 years. Further population-based epidemiological studies specifically focusing on risk factors are needed. The diagnosis of Crohn's disease and therapeutic strategy require improvement.
本文旨在调查中国克罗恩病的住院情况。
收集了1990 - 2003年间中国22个医疗中心的克罗恩病住院病历并进行回顾性分析。每位调查员亲自将每例新发病例详细记录在常规综合资料表格上。对临床表现、检查及治疗情况进行分析。
共发现515例克罗恩病患者。克罗恩病患者占住院患者总数的比例逐年稳步上升。348例患者（67.57%）接受了内镜检查。221例患者（42.91%）接受了钡餐或灌肠检查。340例患者（66.02%）进行了组织学检查（内镜或手术活检）。435例患者（84.47%）采用了合理的治疗策略。54/303例患者（17.82%）的生活质量评估较差。
这项基于医院的回顾性研究表明，在14年的时间里，中国克罗恩病患者数量稳步增加。需要进一步开展针对危险因素的基于人群的流行病学研究。克罗恩病的诊断和治疗策略有待改进。
