初产奶牛产后期间15-酮基-13,14-二氢前列腺素F(2α)的血液水平。

Blood levels of 15-keto-13, 14-dihydroprostaglandin F(2alpha) during the postpartum period in primiparous cows.

作者信息

Madej A, Kindahl H, Woyno W, Edqvist L E, Stupnicki R

机构信息

Department of Clinical Chemistry,Swedish University of Agricultural Sciences S-750 07 Uppsala, Sweden; Laboratory of Growth and Reproductive Physiology Institute of Animal Physiology and Nutrition Polish Academy of Sciences 05-110 Jablonna, Poland.

出版信息

Theriogenology. 1984 Feb;21(2):279-87. doi: 10.1016/0093-691x(84)90413-8.

DOI:10.1016/0093-691x(84)90413-8

PMID:16725878

Abstract

Plasma levels of the PGF(2alpha) metabolite 15-keto-13, 14-dihydroprostaglandin F(2alpha) were determined postpartum in 51 primiparous Black and White Lowland cows. The highest geometric mean was 1702 pmol/l on day 3 and lowest 190 pmol/l on day 21. It should be noted that variation between animals in the concentration of the metabolite is high. For instance, on days 4, 10, 16 and 22, concentration of metabolite ranged from 775-2500, 209-2450, 45-851 and 30-398 pmol/l, respectively. The duration of the massive postpartum release of PGF(2alpha) could be determined in only 29 cows. Significant correlations were found between the duration of elevated PGF(2alpha) metabolite levels and the time required for completion of uterine involution (r = -0.41, P < 0.05) and between the duration of increased PGF(2alpha) metabolite levels and the interval from parturition to occurrence of the first ovulation followed by a normal luteal phase length (r = -0.37, P < 0.05). The occurrence of the first ovulation followed by a normal luteal phase length in the 29 cows was positively correlated with the time needed for completion of uterine involution (r = 0.54, P < 0.01).

摘要

在51头初产黑白花低地奶牛产后测定了血浆中前列腺素F（2α）代谢物15-酮-13，14-二氢前列腺素F（2α）的水平。几何平均数最高值在第3天为1702 pmol/l，最低值在第21天为190 pmol/l。应当指出的是，该代谢物浓度在动物之间的差异很大。例如，在第4、10、16和22天，代谢物浓度分别在775 - 2500、209 - 2450、45 - 851和30 - 398 pmol/l之间。仅在29头奶牛中确定了产后前列腺素F（2α）大量释放的持续时间。发现前列腺素F（2α）代谢物水平升高的持续时间与子宫复旧完成所需时间之间存在显著相关性（r = -0.41，P < 0.05），以及前列腺素F（2α）代谢物水平升高的持续时间与从分娩到首次排卵并伴有正常黄体期长度的间隔之间存在显著相关性（r = -0.37，P < 0.05）。在这29头奶牛中，首次排卵并伴有正常黄体期长度与子宫复旧完成所需时间呈正相关（r = 0.54，P < 0.01）。