Zografos George N, Markou Athina, Ageli Chrisanthi, Kopanakis Nikos, Koutmos Spiros, Kaltsas Gregory, Piaditis George, Papastratis George
Third Department of Surgery, Athens General Hospital G. Gennimatas, Athens, Greece.
Hormones (Athens). 2006 Jan-Mar;5(1):52-6. doi: 10.14310/horm.2002.11168.
Laparoscopic adrenalectomy has rapidly replaced open adrenalectomy as the procedure of choice for benign adrenal tumors. The aim of this study was to evaluate the short- and long-term results of 100 consecutive laparoscopic and open adrenalectomies performed during a period of 8.5 years in our Surgical Unit.
A retrospective analysis of patients operated on for adrenal tumors was conducted. From May 1997 to August 2005, one hundred adrenalectomies were performed on 95 patients. Five patients underwent either synchronous or metachronous bilateral adrenalectomy. There were 38 men and 57 women, aged 16 to 80 years. The size of tumors in our series ranged from 3.2 to 27 cm. The largest laparoscopically excised tumor was a ganglioneuroma with a diameter of 13 cm.
In 73 patients laparoscopic procedure was completed successfully. In 8 cases the laparoscopic procedure was converted to open. Fourteen patients were treated with open approach. One patient with pheochromocytoma succumbed following pulmonary embolus. In one patient with morbid obesity, Cushing's syndrome, and bilateral adrenal macronodular hyperplasia, the left laparoscopic adrenalectomy was complicated by a low output pancreatic fistula, conservatively treated. All other patients had an uneventful course. Operative time for laparoscopic adrenalectomies ranged from 65 to 180 minutes. The average postoperative hospital stay for laparoscopic adrenalectomy ranged from 1 to 2 days (1.5 days), versus 5 to 20 days for patients who underwent open or converted procedure.
Laparoscopic adrenalectomy should be the treatment of choice for all benign adrenal tumors. Laparoscopic resection of large adrenal tumors necessitates experience in open surgery and advanced laparoscopic surgery.
腹腔镜肾上腺切除术已迅速取代开放肾上腺切除术,成为治疗良性肾上腺肿瘤的首选术式。本研究的目的是评估在我们外科病房8.5年期间连续进行的100例腹腔镜和开放肾上腺切除术的短期和长期结果。
对接受肾上腺肿瘤手术的患者进行回顾性分析。1997年5月至2005年8月,对95例患者实施了100例肾上腺切除术。5例患者接受了同期或异期双侧肾上腺切除术。其中男性38例,女性57例,年龄16至80岁。我们系列中肿瘤大小为3.2至27厘米。最大的经腹腔镜切除的肿瘤是直径为13厘米的神经节瘤。
73例患者成功完成了腹腔镜手术。8例患者中转开腹。14例患者采用开放手术治疗。1例嗜铬细胞瘤患者因肺栓塞死亡。1例患有病态肥胖、库欣综合征和双侧肾上腺大结节增生的患者,左侧腹腔镜肾上腺切除术并发低输出量胰瘘,经保守治疗。所有其他患者病程顺利。腹腔镜肾上腺切除术的手术时间为65至180分钟。腹腔镜肾上腺切除术患者的平均术后住院时间为1至2天(1.5天),而接受开放手术或中转手术的患者为5至20天。
腹腔镜肾上腺切除术应是所有良性肾上腺肿瘤的首选治疗方法。腹腔镜切除大肾上腺肿瘤需要有开放手术和高级腹腔镜手术的经验。