Gelfert Carl-Christian, Hauser Simone, Löptien Antje, Montag Nicole, Passmann Mareike, Baumgartner Walter, Staufenbiel Rudolf
Klinik für Wiederkäuer, Department für Nutztiere und Bestandsbetreuung, Veterinärmedizinische Universität Wien.
Berl Munch Tierarztl Wochenschr. 2006 May-Jun;119(5-6):244-50.
In this study, the influence of simultaneous application of anionic salts (AS) and rumen buffer (RB) on the metabolism of dairy cows was examined. Eleven rumen fistulated, non-pregnant and non-lactating dairy cows received equal amounts of one AS (CaCl2 or CaSO4) and one RB (NaHCO3 or KHCO3) via rumen cannula during feeding time over a period of eight days. Before the first application of AS and RB and on day eight of the treatment period, blood, urine and rumen fluid samples were taken. The following parameters were measured: whole blood: pH, base excess, bicarbonate; serum: sodium, potassium, chloride, calcium; urine: pH, net acid base excretion, sodium, potassium, chloride, calcium; rumen fluid: pH. The changes of each parameter were compared via ANOVA. The changes in acid-base balance on day eight were very small, although significant. But p-values showed that the statistical evidence was low. The most changes occurred when NaHCO3 was fed in combination with one of the AS used. In this case a small acidogenic load was seen in blood (p < 0.05), and calcium concentrations increased slightly (p < 0.05). No alkalotic reaction could be detected when any combination of AS and RB were given to the cows. Simultaneous application of AS and RB results in a loss of effectivity of AS. Neither an adequate acidification of blood nor an activation of calcium metabolism occurred. In feed ration for cows in the last weeks of pregnancy, rumen buffer must not be fed, if anionic salts are given for prevention of parturient paresis.
本研究考察了同时施用阴离子盐（AS）和瘤胃缓冲剂（RB）对奶牛新陈代谢的影响。11头装有瘤胃瘘管、未怀孕且未泌乳的奶牛在八天的饲喂期内，于采食时间通过瘤胃套管接受等量的一种AS（氯化钙或硫酸钙）和一种RB（碳酸氢钠或碳酸氢钾）。在首次施用AS和RB之前以及处理期的第八天，采集血液、尿液和瘤胃液样本。测量了以下参数：全血：pH值、碱剩余、碳酸氢盐；血清：钠、钾、氯、钙；尿液：pH值、净酸碱排泄量、钠、钾、氯、钙；瘤胃液：pH值。通过方差分析比较各参数的变化。第八天酸碱平衡的变化非常小，尽管具有显著性。但p值表明统计证据不足。当碳酸氢钠与所使用的一种AS联合投喂时，变化最为明显。在这种情况下，血液中出现了较小的产酸负荷（p < 0.05），钙浓度略有升高（p < 0.05）。给奶牛投喂任何AS和RB的组合时，均未检测到碱中毒反应。同时施用AS和RB会导致AS有效性降低。既未出现血液充分酸化，也未激活钙代谢。在怀孕最后几周的奶牛日粮中，如果为预防生产瘫痪而投喂阴离子盐，则不得投喂瘤胃缓冲剂。
