Tomao Federica, Miele Evelina, Barberi Simona, Caprio Giuliana, Russillol Michelangelo, Spinelli Gian Paolo, La Ferla Giuseppe, Tomao Silverio
Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza, Roma.
Recenti Prog Med. 2006 Apr;97(4):225-8.
Breast cancer presents important differences in distribution of histopathologic factors between younger and older patients but it's less clear if reduction of survival which often occurs in cancer of the youth depends on the concomitant presence of negative prognostic factor or if age alone acts as a factor indicating more aggressiveness. Many studies seem to indicate that young age at diagnosis is an independent predictive factor mostly in patients with early stage of disease and negative nodes. Other studies assert that age can be considered as the most important predictive factor after nodes involvement.
乳腺癌在年轻患者和老年患者的组织病理学因素分布上存在重要差异，但尚不清楚青年癌症患者中常见的生存率降低是取决于同时存在的负面预后因素，还是年龄本身就是表明更具侵袭性的一个因素。许多研究似乎表明，诊断时年龄较小主要是早期疾病且无淋巴结转移患者的一个独立预测因素。其他研究则断言，在出现淋巴结转移后，年龄可被视为最重要的预测因素。
