Lamvu Georgine, Williams Rachel, Zolnoun Denniz, Wechter Mary E, Shortliffe Anne, Fulton Grace, Steege John F
Division of Advanced Laparoscopy and Pelvic Pain, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7508, USA.
Am J Obstet Gynecol. 2006 Aug;195(2):591-8; discussion 598-600. doi: 10.1016/j.ajog.2006.03.081. Epub 2006 May 26.
The purpose of this study was to describe long-term outcomes for women with chronic pelvic pain (CPP) after evaluation in a CPP specialty clinic.
This was a prospective observational cohort study of women treated for CPP at the UNC Pelvic Pain clinic between 1993 and 2000. The primary outcome was improvement in pain and the main exposure was treatment group: primarily medical (pharmacotherapy, psychotherapy, physical therapy, or combinations of the 3) or surgical (hysterectomy, resection or ablative procedures, oophrectomy, diagnostic surgery, pain mapping, vulvar or vestibular repair). Univariate, bivariate, and multivariable analyses were performed to look for relationships between background characteristics, treatment group, and improvement in pain.
Of 370 participants; 189 had surgical treatment and 181 had medical treatment. One year after evaluation, 46% reported improvement in pain and 32% improvement in depression. Improvement in pain was similar in both treatment groups and odds of improvement were equal even after adjusting for background characteristics, psychosocial comorbidity, and previous treatments.
One year after evaluation in a CPP specialty clinic, women experienced modest improvements in pain and depression after recommended surgical or nonsurgical treatment.
本研究旨在描述慢性盆腔疼痛（CPP）女性患者在CPP专科门诊接受评估后的长期结局。
这是一项对1993年至2000年间在北卡罗来纳大学盆腔疼痛诊所接受CPP治疗的女性进行的前瞻性观察队列研究。主要结局是疼痛改善情况，主要暴露因素是治疗组：主要为药物治疗（药物疗法、心理疗法、物理疗法或三者联合）或手术治疗（子宫切除术、切除术或消融手术、卵巢切除术、诊断性手术、疼痛定位、外阴或前庭修复）。进行单变量、双变量和多变量分析以寻找背景特征、治疗组与疼痛改善之间的关系。
370名参与者中，189人接受了手术治疗，181人接受了药物治疗。评估后一年，46%的人报告疼痛有所改善，32%的人抑郁有所改善。两个治疗组的疼痛改善情况相似，即使在调整了背景特征、心理社会合并症和既往治疗后，改善几率也相等。
在CPP专科门诊评估一年后，接受推荐的手术或非手术治疗的女性在疼痛和抑郁方面有适度改善。
