Puertas Alberto, Tirado Pilar, Pérez Isabel, López María S, Montoya Francisco, Cañizares José M, Miranda José A
Obstetrics and Gynaecology Service, Virgen de las Nieves University Hospital, Avenida Fuerzas Armadas s/n, 18014 Granada, Spain.
Obstetrics and Gynaecology Service, Virgen de las Nieves University Hospital, Avenida Fuerzas Armadas s/n, 18014 Granada, Spain.
Eur J Obstet Gynecol Reprod Biol. 2007 Mar;131(1):40-44. doi: 10.1016/j.ejogrb.2006.04.024. Epub 2006 May 26.
To investigate the effect of transcervical amnioinfusion on the management of labour and neonatal outcomes in preterm premature rupture of the membranes.
This clinical trial included 86 patients with premature rupture of the membranes between weeks 27 and 35 of gestation. Patients were randomly assigned to receive amnioinfusion via a two-way catheter or to the control group. Clinical management was otherwise the same in both groups.
Amnioinfusion decreased the frequency of variable decelerations in fetal heart rate (27.9% versus 53.5%, p<0.05) and the rate of obstetric interventions motivated by nonreassuring fetal status (13.6% versus 52.4%, p<0.05). At delivery, pH values were significantly higher in the treatment group than in the conventionally managed control group (median 7.29 versus 7.27).
Intrapartum transcervical amnioinfusion for preterm premature rupture of the membranes reduced the number of interventions needed because of nonreassuring fetal status, and improved neonatal gasometric values without increasing maternal or fetal morbidity.
探讨经宫颈羊膜腔灌注对胎膜早破早产患者分娩管理及新生儿结局的影响。
本临床试验纳入了86例妊娠27至35周胎膜早破的患者。患者被随机分配接受经双向导管进行羊膜腔灌注或进入对照组。两组的临床管理在其他方面相同。
羊膜腔灌注降低了胎儿心率变异减速的频率（27.9%对53.5%，p<0.05）以及因胎儿状况不令人放心而进行产科干预的比率（13.6%对52.4%，p<0.05）。分娩时，治疗组的pH值显著高于传统管理的对照组（中位数7.29对7.27）。
对于胎膜早破早产患者，产时经宫颈羊膜腔灌注减少了因胎儿状况不令人放心而需要进行的干预次数，并改善了新生儿血气指标，且未增加母体或胎儿的发病率。
