Kong Feng-Ming Spring, Zhao Lujun, Hayman James A
Department of Radiation Therapy, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Hematol Oncol Clin North Am. 2006 Apr;20(2):363-400. doi: 10.1016/j.hoc.2006.01.021.
Radiation plays an important role in the treatment of thoracic tumors. During the last 10 years there have been several major advances in thoracic RT including the incorporation of concurrent chemotherapy and the application of con-formal radiation-delivery techniques (eg, stereotactic RT, three-dimensional conformal RT, and intensity-modulated RT) that allow radiation dose escalation. Radiation as a local measure remains the definitive treatment of medically inoperable or surgically unresectable disease in NSCLC and part of a multimodality regimen for locally advanced NSCLC, limited stage SCLC, esophageal cancer, thymoma, and mesothelioma.
放射治疗在胸部肿瘤的治疗中发挥着重要作用。在过去十年中,胸部放疗取得了多项重大进展,包括同步化疗的应用以及适形放疗技术(如立体定向放疗、三维适形放疗和调强放疗)的应用,这些技术可使放射剂量增加。放射治疗作为一种局部治疗手段,仍然是无法进行手术或手术无法切除的非小细胞肺癌的确定性治疗方法,也是局部晚期非小细胞肺癌、局限期小细胞肺癌、食管癌、胸腺瘤和间皮瘤多模式治疗方案的一部分。