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放射治疗在胸部肿瘤中的作用。

The role of radiation therapy in thoracic tumors.

作者信息

Kong Feng-Ming Spring, Zhao Lujun, Hayman James A

机构信息

Department of Radiation Therapy, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

出版信息

Hematol Oncol Clin North Am. 2006 Apr;20(2):363-400. doi: 10.1016/j.hoc.2006.01.021.

DOI:10.1016/j.hoc.2006.01.021
PMID:16730299
Abstract

Radiation plays an important role in the treatment of thoracic tumors. During the last 10 years there have been several major advances in thoracic RT including the incorporation of concurrent chemotherapy and the application of con-formal radiation-delivery techniques (eg, stereotactic RT, three-dimensional conformal RT, and intensity-modulated RT) that allow radiation dose escalation. Radiation as a local measure remains the definitive treatment of medically inoperable or surgically unresectable disease in NSCLC and part of a multimodality regimen for locally advanced NSCLC, limited stage SCLC, esophageal cancer, thymoma, and mesothelioma.

摘要

放射治疗在胸部肿瘤的治疗中发挥着重要作用。在过去十年中,胸部放疗取得了多项重大进展,包括同步化疗的应用以及适形放疗技术(如立体定向放疗、三维适形放疗和调强放疗)的应用,这些技术可使放射剂量增加。放射治疗作为一种局部治疗手段,仍然是无法进行手术或手术无法切除的非小细胞肺癌的确定性治疗方法,也是局部晚期非小细胞肺癌、局限期小细胞肺癌、食管癌、胸腺瘤和间皮瘤多模式治疗方案的一部分。

相似文献

1
The role of radiation therapy in thoracic tumors.放射治疗在胸部肿瘤中的作用。
Hematol Oncol Clin North Am. 2006 Apr;20(2):363-400. doi: 10.1016/j.hoc.2006.01.021.
2
The role of radiation therapy in non-small cell lung cancer.放射治疗在非小细胞肺癌中的作用。
Semin Respir Crit Care Med. 2005 Jun;26(3):278-88. doi: 10.1055/s-2005-871986.
3
[Radiation therapy for lung cancer].[肺癌的放射治疗]
Gan To Kagaku Ryoho. 2007 Apr;34(4):544-9.
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A phase I study of pemetrexed, carboplatin, and concurrent radiotherapy in patients with locally advanced or metastatic non-small cell lung or esophageal cancer.培美曲塞、卡铂及同步放疗用于局部晚期或转移性非小细胞肺癌或食管癌患者的I期研究。
Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):515-22. doi: 10.1158/1078-0432.CCR-06-1058.
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[Radiotherapy in malignant lung tumors].[恶性肺肿瘤的放射治疗]
Ther Umsch. 1994 Apr;51(4):262-6.
6
[Initial outcome of induction chemotherapy with weekly paclitaxel followed by three-dimensional conformal radiotherapy and concurrent weekly paclitaxel for stage III non-small cell lung cancer].[III期非小细胞肺癌患者先行每周一次紫杉醇诱导化疗,随后进行三维适形放疗并同步每周一次紫杉醇治疗的初步结果]
Ai Zheng. 2006 Oct;25(10):1279-83.
7
[Chemoradiation for locally advanced non-small cell lung cancer].[局部晚期非小细胞肺癌的放化疗]
Cancer Radiother. 2007 Jan-Feb;11(1-2):67-76. doi: 10.1016/j.canrad.2006.11.002. Epub 2007 Jan 5.
8
Modern radiotherapy as part of combined modality treatment in locally advanced non-small cell lung cancer: present status and future prospects.现代放射治疗作为局部晚期非小细胞肺癌综合治疗模式的一部分:现状与未来展望。
Oncologist. 2008 Jun;13(6):700-8. doi: 10.1634/theoncologist.2007-0196.
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[Stage IIIB non-small cell lung cancer. Optimization of radiotherapy in lung cancer: some interesting questions to be solved].[ⅢB期非小细胞肺癌。肺癌放疗的优化:一些有待解决的有趣问题]
Rev Mal Respir. 2006 Nov;23(5 Pt 3):16S61-16S67.
10
High-dose radiotherapy for the treatment of inoperable non-small cell lung cancer.高剂量放射疗法治疗不可切除的非小细胞肺癌。
Cancer J. 2007 Jul-Aug;13(4):238-42. doi: 10.1097/PPO.0b013e31813ffd7b.

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Tissue TGF-β expression following conventional radiotherapy and pulsed low-dose-rate radiation.
常规放疗和脉冲低剂量率放疗后组织 TGF-β 的表达。
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Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis.转化生长因子β(TGFβ)和血小板衍生生长因子(PDGF)信号通路的联合抑制可减轻辐射诱导的肺纤维化。
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Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice.2-氰基-3,12-二氧代齐墩果-1,9-二烯-28-酸C-28甲酯(CDDO-Me;巴多索隆甲酯)对小鼠辐射诱导的肺部炎症和纤维化的治疗作用。
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