von Kamp Axel, Schuster Stefan
Department of Bioinformatics, Friedrich-Schiller-University Jena 07743 Jena, Germany.
Bioinformatics. 2006 Aug 1;22(15):1930-1. doi: 10.1093/bioinformatics/btl267. Epub 2006 May 26.
Elementary modes analysis is a powerful tool in the constraint-based modeling of metabolic networks. In recent years, new approaches to calculating elementary modes in biochemical reaction networks have been developed. As a consequence, the program Metatool, which is one of the first programs dedicated to this purpose, has been reimplemented in order to make use of these new approaches. The performance of Metatool has been significantly increased and the new version 5.0 can now be run inside the GNU octave or Matlab environments to allow more flexible usage and integration with other tools.
The script files and compiled shared libraries can be downloaded from the Metatool website at http://pinguin.biologie.uni-jena.de/bioinformatik/networks/index.html. Metatool consists of script files (m-files) for GNU octave as well as Matlab and shared libraries. The scripts are licensed under the GNU Public License and the use of the shared libraries is free for academic users and testing purposes. Commercial use of Metatool requires a special contract.
基本模式分析是代谢网络基于约束建模中的一种强大工具。近年来，已开发出计算生化反应网络中基本模式的新方法。因此，作为最早致力于此目的的程序之一的Metatool程序已被重新实现，以便利用这些新方法。Metatool的性能已显著提高，新版本5.0现在可以在GNU octave或Matlab环境中运行，以实现更灵活的使用并与其他工具集成。
脚本文件和编译后的共享库可从Metatool网站http://pinguin.biologie.uni-jena.de/bioinformatik/networks/index.html下载。Metatool由用于GNU octave以及Matlab的脚本文件（m文件）和共享库组成。脚本遵循GNU公共许可证许可，学术用户出于测试目的可免费使用共享库。Metatool的商业使用需要特殊合同。
