Xavier Daniela, Vázquez Sara, Higuera Clara, Morán Federico, Montero Francisco
Departamento de Bioquímica y Biología Molecular I, Universidad Complutense Madrid, Avd. Complutense s/n, 28040 Madrid, Spain.
Biosystems. 2011 Aug;105(2):169-72. doi: 10.1016/j.biosystems.2011.04.004. Epub 2011 Apr 21.
Tools-4-Metatool (T4M) is a suite of web-tools, implemented in PERL, which analyses, parses, and manipulates files related to Metatool. Its main goal is to assist the work with Metatool. T4M has two major sets of tools: Analysis and Compare. Analysis visualizes the results of Metatool (convex basis, elementary flux modes, and enzyme subsets) and facilitates the study of metabolic networks. It is composed of five tools: MDigraph, MetaMatrix, CBGraph, EMGraph, and SortEM. Compare was developed to compare different Metatool results from different networks. This set consists of: Compara and ComparaSub which compare network subsets providing outputs in different formats and ComparaEM that seeks for identical elementary modes in two metabolic networks. The suite T4M also includes one script that generates Metatool input: CBasis2Metatool, based on a Metatool output file that is filtered by a list of convex basis' metabolites. Finally, the utility CheckMIn checks the consistency of the Metatool input file. T4M is available at http://solea.quim.ucm.es/t4m.
工具4元工具（T4M）是一套用PERL语言实现的网络工具，用于分析、解析和处理与元工具相关的文件。其主要目标是辅助元工具的工作。T4M有两大主要工具集：分析和比较。分析工具用于可视化元工具的结果（凸基、基本通量模式和酶子集），并促进对代谢网络的研究。它由五个工具组成：MDigraph、MetaMatrix、CBGraph、EMGraph和SortEM。比较工具集是为比较来自不同网络的不同元工具结果而开发的。该工具集包括：Compara和ComparaSub，用于比较网络子集并以不同格式提供输出；以及ComparaEM，用于在两个代谢网络中寻找相同的基本模式。T4M套件还包括一个基于通过凸基代谢物列表过滤的元工具输出文件生成元工具输入的脚本：CBasis2Metatool。最后，实用程序CheckMIn检查元工具输入文件的一致性。T4M可在http://solea.quim.ucm.es/t4m获取。
