Ng M, Wirth A, Ryan G, MacManus M, Davis S
Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Australas Radiol. 2006 Jun;50(3):222-7. doi: 10.1111/j.1440-1673.2006.01566.x.
Low-dose radiotherapy over the last decade has been reported to provide effective palliation for patients with low-grade non-Hodgkin's lymphoma. In this retrospective case series of 10 patients, we report our early experience using low-dose radiotherapy (usually 2 x 2 Gy) for patients with advanced-stage follicular, mucosal associated lymphoid tissue, mantle cell and small lymphocytic lymphomas. Median follow up was 27 weeks. Response rates were high (complete response, 70%; partial response, 20%), the response durable and the toxicity was minimal (no toxicity greater than grade 1). Low-dose irradiation is an effective treatment option for patients with low-grade lymphomas with local symptoms.
据报道，在过去十年中，低剂量放疗可为低度非霍奇金淋巴瘤患者提供有效的姑息治疗。在这个包含10例患者的回顾性病例系列中，我们报告了对晚期滤泡性、黏膜相关淋巴组织、套细胞和小淋巴细胞淋巴瘤患者使用低剂量放疗（通常为2×2 Gy）的早期经验。中位随访时间为27周。缓解率很高（完全缓解率为70%；部分缓解率为20%），缓解持续，毒性极小（无大于1级的毒性）。低剂量照射是有局部症状的低度淋巴瘤患者的一种有效治疗选择。
