参与极化运输和轴突生长的驱动蛋白调节因子。
Regulators of kinesin involved in polarized trafficking and axon outgrowth.
作者信息
Luo Shuo, Nonet Michael L
机构信息
Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 S, Euclid Avenue, Saint Louis, MO 63110, USA.
出版信息
J Biol. 2006;5(4):8. doi: 10.1186/jbiol41. Epub 2006 May 25.
Abstract
Proteins such as UNC-76 that associate with kinesin motors are important in directing neurite extension. A small Caenorhabditis elegans coiled-coil protein, UNC-69, has now been shown to interact with UNC-76 and to be involved in axonal (but not dendritic) transport and outgrowth, as well as synapse formation.
摘要
诸如UNC-76这类与驱动蛋白马达相关的蛋白质在引导神经突延伸过程中起着重要作用。现已证明，一种小型秀丽隐杆线虫卷曲螺旋蛋白UNC-69可与UNC-76相互作用，并参与轴突（而非树突）运输、生长以及突触形成。
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