Mor Felix, Monsonego Alon
Tel-Aviv University, Weizmann Institute of Science Department of Immunology, Rehovot, Israel.
Expert Rev Neurother. 2006 May;6(5):653-9. doi: 10.1586/14737175.6.5.653.
Alzheimer's disease (AD) is a common and devastating neurodegenerative disease. The incidence of AD is increasing in Western societies. The current treatment of AD is mostly symptomatic and ineffective in stopping or reversing the cognitive impairment. One of the exciting and effective new treatments developed in experimental AD is immunization against amyloid-beta peptide. This article provides an overview of immunization therapy in AD and examines the future prospects of this therapeutic modality.
阿尔茨海默病（AD）是一种常见且具有毁灭性的神经退行性疾病。在西方社会，AD的发病率正在上升。目前AD的治疗大多只是对症治疗，在阻止或逆转认知障碍方面无效。在实验性AD中开发的一种令人兴奋且有效的新治疗方法是针对β-淀粉样肽进行免疫接种。本文概述了AD中的免疫治疗，并探讨了这种治疗方式的未来前景。
