Ku Ja Hyeon, Oh Jin Gyu, Shin Jae Wook, Kim Soo Woong, Paick Jae-Seung
Department of Urology, Seoul National University College of Medicine, Seoul, Korea.
Int J Urol. 2006 Apr;13(4):379-84. doi: 10.1111/j.1442-2042.2006.01302.x.
The objective of this study was to determine whether the outcome of mid-urethral sling procedures is influenced by the body mass index of Korean women suffering from stress urinary incontinence (SUI).
A total of 285 women, ranging in age from 28 to 80 years (mean 55.4), all of whom were followed up for at least 6 months, were ultimately included in this study. The patients were classified as follows: normal weight, 18.5-23 kg/m2; overweight, 23-27.5 kg/m2; obesity, 27.5 kg/m2 or higher.
We noted bladder perforations in 11 cases (4.9%, 3.8% and 2.2% in the normal weight, overweight, and obesity groups, respectively; P = 0.449). We determined there to be no significant differences among the three groups with regard to cure rate (P = 0.173). The rates of postoperative urinary retention were 9.9% in the normal weight group, 10.1% in the overweight group, and 15.6% in the obesity group (P = 0.396). We determined there to be no significant differences among the three groups with regard to the persistence of urgency (P = 0.312). Seventy-nine patients (27.7%) exhibited symptoms indicative of voiding disorder (hesitancy, poor flow, or sensations of incomplete emptying). The postoperative development of these voiding symptoms was not significantly different among the three groups (P = 0.106).
Our results demonstrate both the feasibility and the safety of mid-urethral sling procedures for obese Korean women who suffer from SUI. Additional studies, including prospective randomized trials with longer follow-up periods, will be required in order to confirm these findings.
本研究的目的是确定体重指数是否会影响患有压力性尿失禁(SUI)的韩国女性的中段尿道吊带手术效果。
本研究最终纳入了285名年龄在28至80岁(平均55.4岁)之间的女性,所有患者均接受了至少6个月的随访。患者分类如下:正常体重,18.5 - 23kg/m²;超重,23 - 27.5kg/m²;肥胖,27.5kg/m²及以上。
我们注意到11例膀胱穿孔(正常体重、超重和肥胖组分别为4.9%、3.8%和2.2%;P = 0.449)。我们确定三组在治愈率方面无显著差异(P = 0.173)。正常体重组术后尿潴留率为9.9%,超重组为10.1%,肥胖组为15.6%(P = 0.396)。我们确定三组在尿急持续存在方面无显著差异(P = 0.312)。79名患者(27.7%)表现出排尿障碍症状(犹豫、尿流不畅或排空不全感)。三组术后这些排尿症状的发生情况无显著差异(P = 0.106)。
我们的结果表明,中段尿道吊带手术对于患有SUI的肥胖韩国女性既可行又安全。需要进行更多研究,包括随访期更长的前瞻性随机试验来证实这些发现。