Márquez-Martín E, Valera-Bestard B, Luque-Márquez R, Alarcón-González A
Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Arch Bronconeumol. 2006 Apr;42(4):202-4. doi: 10.1016/s1579-2129(06)60443-6.
We reviewed a series of 5 cases of leptospirosis treated in our hospital between 1998 and 2004 and found that lung involvement was observed in 3 of the 5 cases. All patients met the criteria for the diagnosis of leptospirosis. Weil syndrome was diagnosed in 4 patients and anicteric leptospirosis in 1 patient. The 3 patients with lung sequelae were admitted into the intensive care unit because of severe respiratory failure. All patients responded to antibiotic treatment; 3 received doxycycline and 2 received doxycycline with penicillin G. Leptospirosis can lead to severe lung complications often requiring admission to the intensive care unit. The degree of severity is independent of the particular clinical syndrome (the anicteric form or Weil syndrome). Finally, despite the severity of the clinical picture, our patients responded to medical treatment and did not require invasive mechanical ventilation.
我们回顾了1998年至2004年在我院接受治疗的5例钩端螺旋体病病例,发现5例中有3例出现肺部受累。所有患者均符合钩端螺旋体病的诊断标准。4例患者被诊断为韦尔综合征,1例为无黄疸型钩端螺旋体病。3例有肺部后遗症的患者因严重呼吸衰竭入住重症监护病房。所有患者对抗生素治疗均有反应;3例接受强力霉素治疗,2例接受强力霉素联合青霉素G治疗。钩端螺旋体病可导致严重的肺部并发症,常需入住重症监护病房。严重程度与特定临床综合征(无黄疸型或韦尔综合征)无关。最后,尽管临床表现严重,但我们的患者对药物治疗有反应,无需有创机械通气。