Colvard Michael D, Cordell Geoffrey A, Villalobos Rodrigo, Sancho Gina, Soejarto Doel D, Pestle William, Echeverri Tatiana Lobo, Perkowitz Kathleen M, Michel Joanna
Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois at Chicago, 60612, USA.
J Ethnopharmacol. 2006 Aug 11;107(1):134-42. doi: 10.1016/j.jep.2006.04.005. Epub 2006 Apr 18.
Ethnomedical questionnaires were distributed in Chicago, Costa Rica, and Colombia to identify the most common over-the-counter (OTC) plant or plant-based products advocated for treating oral pain, ulcerative conditions, and cancer within these locations. Over 100 plants or plant-based herbal preparations and commercial products, purchased from local botanical markets and pharmacies, were advocated for the treatment of oral medicine conditions. Locally familiar and common language names were attributed to the plant products at the time of purchase. Plant products or plant-based commercial products containing plant-based essential oils, anesthetic constituents, and or chemical compounds recommended as OTC oral medicine preparations were systematized, tabulated, and correlated with the published phytotherapeutic literature. Though pharmacognostic research is available for some of the species collected, further ethnographic research is needed to correlate common names with the accurate taxonomic identification for each plant species. Furthermore, epidemiological research is needed to verify the use and standardized dosage for OTC ethnomedicine preparations for oral medicine conditions. Pharmacognostic research and clinical trails which can verify taxonomy, dose, safety, active principles, and efficacy of these OTC oral medicine products must be enhanced in order to verify the claimed validity in contemporary, global, oral medicine practice.
民族医学调查问卷在芝加哥、哥斯达黎加和哥伦比亚发放，以确定在这些地区被提倡用于治疗口腔疼痛、溃疡性疾病和癌症的最常见非处方（OTC）植物或植物性产品。从当地植物市场和药店购买了100多种植物或植物性草药制剂及商业产品，它们被提倡用于治疗口腔疾病。购买时，根据当地熟悉的通用语言为植物产品命名。将含有植物性精油、麻醉成分和/或被推荐作为非处方口服药制剂的化合物的植物产品或植物性商业产品进行系统化、列表，并与已发表的植物治疗文献相关联。虽然对一些采集到的物种已有生药学研究，但仍需要进一步的人种学研究，以便将通用名称与每种植物物种的准确分类鉴定相关联。此外，还需要进行流行病学研究，以核实非处方民族药制剂在口腔疾病治疗中的使用情况和标准化剂量。必须加强能够核实这些非处方口服药产品的分类学、剂量、安全性、活性成分和疗效的生药学研究和临床试验，以证实其在当代全球口腔医学实践中所宣称的有效性。
