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腹腔镜辅助远端胃切除术与开放远端胃切除术的比较研究

Comparative study of laparoscopy-assisted distal gastrectomy and open distal gastrectomy.

作者信息

Lee Sang-Il, Choi Yoo-Shin, Park Do Joong, Kim Hyung-Ho, Yang Han-Kwang, Kim Min-Chan

机构信息

Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.

出版信息

J Am Coll Surg. 2006 Jun;202(6):874-80. doi: 10.1016/j.jamcollsurg.2006.02.028.

Abstract

BACKGROUND

Most studies comparing surgical results of laparoscopic procedures for gastric cancer with open gastrectomies have been conducted based on limited experience. We aimed to compare laparoscopy-assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) after a protracted learning experience.

STUDY DESIGN

We retrospectively reviewed medical records data. Two hundred fifty six patients underwent distal gastrectomies (136 LADG, 120 ODG). There were 150 early gastric cancer (EGC) patients (120 LADG, 30 ODG).

RESULTS

Mean operation times for LADG and ODG were similar among EGC (156.5 versus 159.3 minutes, p = 0.666). Mean retrieved lymph node counts for LADG and ODG were different, but were > 30 (31.3 versus 40.4 for all and 30.4 versus 38.1 for EGC). For all subjects or EGC patients after LADG, C-reactive proteins on day 5 were substantially lower, first liquid diet was resumed substantially sooner, and postoperative hospital stays were substantially shorter than for ODG.

CONCLUSIONS

LADG with lymph node dissection after a learning curve has several advantages compared with ODG, namely, less inflammatory reaction, rapid return of gastrointestinal function, and shorter hospital stay without compromising operation time or operative curability.

摘要

背景

大多数比较腹腔镜胃癌手术与开放胃切除术手术结果的研究都是基于有限的经验进行的。我们旨在经过长期学习经验后比较腹腔镜辅助远端胃切除术(LADG)和传统开放远端胃切除术(ODG)。

研究设计

我们回顾性分析了病历数据。256例患者接受了远端胃切除术(136例行LADG,120例行ODG)。其中有150例早期胃癌(EGC)患者(120例行LADG,30例行ODG)。

结果

在EGC患者中,LADG和ODG的平均手术时间相似(156.5分钟对159.3分钟,p = 0.666)。LADG和ODG的平均回收淋巴结数不同,但均> 30(所有患者中分别为31.3对40.4,EGC患者中为30.4对38.1)。对于LADG后的所有受试者或EGC患者,术后第5天的C反应蛋白显著更低,首次恢复流食显著更早,术后住院时间显著短于ODG。

结论

经过学习曲线后的LADG淋巴结清扫术与ODG相比有几个优点,即炎症反应更小、胃肠功能恢复快、住院时间短,且不影响手术时间或手术可治愈性。

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