Hanada Satoshi, Kawakami Hiromasa, Goto Takahisa, Morita Shigeho
Department of Anesthesiology, Teikyo University School of Medicine, Itabashi-ku, Tokyo, Japan.
Curr Opin Anaesthesiol. 2006 Jun;19(3):315-9. doi: 10.1097/01.aco.0000192811.56161.23.
There are still many controversies about perioperative management of hypertensive patients. This review aims to provide relevant instruction based on evidence regarding the treatment of those patients.
Mild to moderate hypertension is not independently responsible for perioperative cardiac complications. The position is less clear for severely hypertensive patients. A randomized study shows no benefit of the traditional practice of delaying elective surgery in severely hypertensive patients until better control of blood pressure is achieved. Perioperative use of beta-blockers or alpha-2 agonists has been shown to maintain perioperative hemodynamic stability and thereby to prevent major cardiac complications.
Delaying surgery only for the purpose of blood pressure control may not be necessary, especially in the case of mild to moderate hypertension. Strict care, however, should be taken to ensure perioperative hemodynamic stability because labile hemodynamics, rather than preoperative hypertension per se, appears to be more closely associated with adverse cardiovascular complications. Delaying surgery in hypertensive patients may be justified if target organ damage exists that can be improved by such a delay or if (suspected) target organ damage should be evaluated further before the operation.
高血压患者围手术期管理仍存在诸多争议。本综述旨在基于相关证据为这些患者的治疗提供指导。
轻至中度高血压并非围手术期心脏并发症的独立危险因素。重度高血压患者的情况尚不清楚。一项随机研究表明,将择期手术推迟至重度高血压患者血压得到更好控制这一传统做法并无益处。围手术期使用β受体阻滞剂或α₂激动剂已被证明可维持围手术期血流动力学稳定,从而预防重大心脏并发症。
仅为控制血压而推迟手术可能并无必要,尤其是对于轻至中度高血压患者。然而,应严格注意确保围手术期血流动力学稳定,因为不稳定的血流动力学,而非术前高血压本身,似乎与不良心血管并发症的关系更为密切。如果存在可通过推迟手术改善的靶器官损害,或如果在手术前应进一步评估(疑似)靶器官损害,则推迟高血压患者的手术可能是合理的。