Forer Boaz, Vasilyev Tamar, Brosh Tamar, Kariv Naam, Trejo Leonor Leider, Gil Ziv, Katzir Abraham, Fliss Dan M
Department of Otolaryngology Head and Neck Surgery, Tel-Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
Laryngoscope. 2006 Jun;116(6):1002-6. doi: 10.1097/01.mlg.0000217241.01388.2d.
HYPOTHESIS/OBJECTIVES: We tested the effectiveness of a temperature-controlled CO2 laser soldering system on a porcine model for dural defect reconstruction using a fascial patch.
A dural patch was excised and then reconstructed with fascia by a CO2 laser system in vitro in 27 animals and in vivo in five animals.
After dural reconstruction, the average burst pressure of the soldered patch in vitro, as measured by a custom-made pressure detector, was 258.5 cm H2O. All five pigs in the in vivo group showed no neurological complications or cerebrospinal fluid leak, and the underlying brain tissue showed no thermal injury.
The CO2 laser system created a watertight bond and did not cause thermal injury to the brain. The procedure is potentially faster than conventional repair, and wound healing may also be more rapid.
假设/目的：我们在猪模型上测试了一种温控二氧化碳激光焊接系统，该系统使用筋膜补片进行硬脑膜缺损重建。
在27只动物体外以及5只动物体内，用二氧化碳激光系统切除硬脑膜补片，然后用筋膜进行重建。
硬脑膜重建后，通过定制压力探测器测量，体外焊接补片的平均破裂压力为258.5厘米水柱。体内组的所有5只猪均未出现神经并发症或脑脊液漏，且下方脑组织未出现热损伤。
二氧化碳激光系统形成了防水密封，且未对大脑造成热损伤。该手术可能比传统修复更快，伤口愈合也可能更快。
