Couvelard Anne
Service d'Anatomie Pathologique, Hôpital Beaujon, APHP - Université Paris 7, 100 Boulevard du Général Leclerc, 92110 Clichy.
Ann Pathol. 2005 Dec;25(6):499-509. doi: 10.1016/s0242-6498(05)86163-2.
Gastro-intestinal endocrine tumors constitute a heterogeneous group of tumors. Their clinical features, functional properties, and clinical course differ according to their site of origin. From a practical point of view, several topographical groups may be distinguished: (a) stomach, (b) duodenum and proximal jejunum, (c) ileum and caecum, (d) appendix, (a) colon and rectum. In each of these groups, a certain degree of tumor heterogeneity persists, especially between colon and rectal tumors, which would be better considered apart. In this review, we will describe the main functional, morphological and evolutive features of endocrine tumors in each of the topographical groups currently recognized.
胃肠道内分泌肿瘤构成了一组异质性肿瘤。它们的临床特征、功能特性和临床病程因其起源部位而异。从实际角度来看，可以区分出几个不同的部位组：（a）胃，（b）十二指肠和空肠近端，（c）回肠和盲肠，（d）阑尾，（e）结肠和直肠。在这些组中的每一组中，都存在一定程度的肿瘤异质性，尤其是结肠和直肠肿瘤之间，最好将它们分开考虑。在这篇综述中，我们将描述目前公认的每个部位组中内分泌肿瘤的主要功能、形态和演变特征。
