Ahmed Mohamed A T, Duncan Martin, Kent Alison
Department of Neonatology, The Center for Newborn Care, The Canberra Hospital, and The ANU Medical School, Canberra, Australian Capital Territory, Australia.
J Paediatr Child Health. 2006 Jun;42(6):337-40. doi: 10.1111/j.1440-1754.2006.00868.x.
To ascertain the prevalence of significant Retinopathy of Prematurity (ROP) and ROP requiring treatment in infants born greater than 30 weeks gestation and with a birthweight greater than 1250 g, utilising the Neonatal Intensive Care Units' (NICUS) data collection from 1998 to 2002. Second, to determine whether infants delivered at more than 30 weeks gestation or with a birthweight greater than 1250 g require ROP screening.
A review of the New South Wales and Australian Capital Territory NICUS data collection from 1998 to 2002 was performed. Infants of gestational age 31-33 weeks and with a birthweight greater than 1250 g were included. A review was performed of these infants to ascertain stage of ROP, threshold disease and treatment for ROP.
2292 infants were greater than 30 weeks and had a birthweight greater than 1250 g. Of these 1386 (60%) were not examined or died prior to eye examination. No ROP was noted in 888 of the 904 infants examined (98%), 13 infants had stage 1 (1.4%), five infants stage 2 (0.6%) and no infant had stage 3 ROP. No infant developed stage 3 ROP, required treatment for ROP or had threshold disease.
In this regional study of infants greater than 30 weeks gestation and with a birthweight greater than 1250 g, the prevalence of any ROP was low (2.0%). This study supports evidence from other studies that screening for ROP could be restricted, at least within our referral network, to infants less than 30 completed weeks and a birthweight less than 1250 g.
利用1998年至2002年新生儿重症监护病房（NICUS）的数据收集，确定孕周大于30周且出生体重超过1250克的婴儿中严重早产儿视网膜病变（ROP）及需要治疗的ROP的患病率。其次，确定孕周超过30周或出生体重超过1250克的婴儿是否需要进行ROP筛查。
对新南威尔士州和澳大利亚首都地区1998年至2002年的NICUS数据收集进行回顾。纳入孕周为31 - 33周且出生体重超过1250克的婴儿。对这些婴儿进行回顾以确定ROP分期、阈值疾病及ROP治疗情况。
2292名婴儿孕周大于30周且出生体重超过1250克。其中1386名（60%）未接受检查或在眼科检查前死亡。在接受检查的904名婴儿中，888名（98%）未发现ROP，13名婴儿为1期（1.4%），5名婴儿为2期（0.6%），无婴儿为3期ROP。无婴儿发展为3期ROP、需要进行ROP治疗或患有阈值疾病。
在这项针对孕周大于30周且出生体重超过1250克婴儿的地区性研究中，任何ROP的患病率较低（2.0%）。本研究支持其他研究的证据，即ROP筛查至少在我们的转诊网络内可局限于孕周未满30周且出生体重小于1250克的婴儿。
