RNA干扰在调控果蝇端粒中发挥作用。

Casacuberta Elena, Pardue Mary-Lou

ICREA, IBMB-CSIC, Parc Científic de Barcelona, Josep Samitier 1-5, Barcelona 08028, Spain.

Genome Biol. 2006;7(5):220. doi: 10.1186/gb-2006-7-5-220. Epub 2006 May 31.

Unlike many other organisms, Drosophila maintains its telomeres by the transposition of retrotransposons to chromosome ends. Recent work shows that proteins in the RNA interference pathway specifically regulate the expression of these retrotransposons and frequency of transposition in germline cells, but do not affect retrotransposon expression or telomere function in the soma.

与许多其他生物不同，果蝇通过反转录转座子向染色体末端的转座来维持其端粒。最近的研究表明，RNA干扰途径中的蛋白质特异性地调节这些反转录转座子在生殖细胞中的表达和转座频率，但不影响体细胞中反转录转座子的表达或端粒功能。

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Casacuberta Elena, Pardue Mary-Lou

ICREA, IBMB-CSIC, Parc Científic de Barcelona, Josep Samitier 1-5, Barcelona 08028, Spain.

Genome Biol. 2006;7(5):220. doi: 10.1186/gb-2006-7-5-220. Epub 2006 May 31.

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RNA干扰在调控果蝇端粒中发挥作用。

RNA interference has a role in regulating Drosophila telomeres.

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