Mitchell J M, Wheeler W S
Department of Emergency Medicine, East Carolina University School of Medicine/Pitt County, Memorial Hospital, Greenville, North Carolina 27858-4354.
Ann Emerg Med. 1991 May;20(5):540-8. doi: 10.1016/s0196-0644(05)81612-9.
Emergency care of patients with acute myocardial infarction requires active decision making to use agents that may improve morbidity and mortality. Thrombolysis remains the primary tool to accomplish this goal. Other pharmacologic agents, including lidocaine, nitrates, calcium channel blockers, beta-blockers, and aspirin, have been used acutely in myocardial infarction in the hopes of preventing death and salvaging myocardium. The decision to select one or all of these agents requires a knowledge of the clinical evidence of their efficacy and risk-to-benefit ratios. The clinical studies of the use of these agents acutely in the management of myocardial infarction are reviewed.
急性心肌梗死患者的急诊护理需要积极做出决策，以使用可能改善发病率和死亡率的药物。溶栓仍然是实现这一目标的主要手段。其他药物，包括利多卡因、硝酸盐、钙通道阻滞剂、β受体阻滞剂和阿司匹林，已在心肌梗死急性期使用，以期预防死亡和挽救心肌。选择使用其中一种或所有这些药物需要了解其疗效的临床证据以及风险效益比。本文综述了这些药物在心肌梗死急性期管理中的临床研究。
