Schäfer H, Schneider P M, Baldus S E, Wolfgarten E, Hölscher A H
Klinik und Poliklinik für Viszeral- und Gefässchirurgie der Universität zu Köln.
Zentralbl Chir. 2006 Jun;131(3):206-9. doi: 10.1055/s-2006-933463.
Surgical therapy of Gastrointestinal stroma tumor (GIST) is the treatment of choice. Local resection will be carried out if technically possible. We describe the technique of laparoscopic wedge resection combined with intraoperative gastroscopy in order to achieve complete tumor resection.
We report on 4 cases with gastrointestinal stroma tumors which were located in the gastric corpus (n = 2) and the cardia (n = 2).
In all patients the tumor could be removed completely without any perioperative complications using laparoscopic wedge resection controlled by intraoperative endoscopy. The duration of hospitalisation after operation was 7 days (5-10). On the basis of the mean tumor size (mean 3.8 cm) and the low mitotic activity (mean 2.75/high power fields) the tumors belong to the group with low malignant potential. There is no evidence of recurrence after a mean follow up period of 23 (6-30) months.
Combined laparoscopic/endoscopic wedge resection is a safe method for total resection of GIST of the stomach and should be preferred as alternative to open surgery.
胃肠道间质瘤（GIST）的手术治疗是首选治疗方法。若技术可行，将进行局部切除。我们描述了腹腔镜楔形切除术联合术中胃镜检查以实现肿瘤完全切除的技术。
我们报告了4例胃肠道间质瘤患者，肿瘤分别位于胃体部（2例）和贲门部（2例）。
所有患者均通过术中内镜控制的腹腔镜楔形切除术完全切除肿瘤，无任何围手术期并发症。术后住院时间为7天（5 - 10天）。基于平均肿瘤大小（平均3.8 cm）和低有丝分裂活性（平均2.75/高倍视野），这些肿瘤属于恶性潜能低的组。平均随访23个月（6 - 30个月）后无复发迹象。
腹腔镜/内镜联合楔形切除术是胃GIST全切除的一种安全方法，应优先作为开放手术的替代方法。
