Outin Hervé, Fangio Pascal
Service de reanimation médicale, centre hospitalier de Poissy/Saint-Germain-en-Laye, 10, rue du Champ Gaillard, 78303 Poissy.
Rev Prat. 2006 Apr 15;56(7):746-53.
Altered states of consciousness are a common reason for visits to the emergency room and admission to intensive care unit. Management of unconscious patient can be difficult because the potential causes of an altered mental status are considerable and the time for diagnosis and effective intervention is short. First, the patient must airway, breathing, and circulation protected. It is important to obtain carefully taken history from eyewitnesses and to perform a general complete examination particularly neurologic focusing on pupillary responses, eye movements, and motor responses. Technical investigations like CT-scan and laboratory tests should make part of a careful diagnostic plan. The prognosis for recovery depends greatly on the underlying etiology as well as its optimal treatment, which seeks to preserve neurologic function and maximize the potential for recovery by reversing the primary cause of brain injury, if known, and preventing secondary brain injury from anoxia, ischemia, hypoglycemia, cerebral edema, and electrolyte disturbances.
意识状态改变是患者前往急诊室就诊和入住重症监护病房的常见原因。对昏迷患者的管理可能具有挑战性,因为导致精神状态改变的潜在原因众多,且诊断和有效干预的时间紧迫。首先,必须保护患者的气道、呼吸和循环。从目击者处仔细获取病史,并进行全面的体格检查,尤其是神经系统检查,重点关注瞳孔反应、眼球运动和运动反应,这一点很重要。CT扫描等技术检查和实验室检查应成为审慎诊断计划的一部分。恢复的预后很大程度上取决于潜在病因及其最佳治疗,治疗旨在保留神经功能,并通过逆转已知的脑损伤主要原因以及预防缺氧、缺血、低血糖、脑水肿和电解质紊乱导致的继发性脑损伤,来最大化恢复潜力。