Shaham Shai
The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.
Dev Cell. 2006 Jun;10(6):690-1. doi: 10.1016/j.devcel.2006.05.002.
Engulfment of dying cells plays an important role during animal development and homeostasis, and several proteins involved in this process are known. However, the cell biology underlying phagocyte arm extension and cell corpse degradation is not well understood. A study published in this issue of Developmental Cell (Yu et al., 2006) now demonstrates an important role for the GTPase dynamin in these events.
吞噬凋亡细胞在动物发育和体内平衡过程中发挥着重要作用,并且已知有几种蛋白质参与这一过程。然而,吞噬细胞臂伸展和细胞尸体降解背后的细胞生物学机制尚未得到充分了解。发表在本期《发育细胞》(Yu等人,2006年)上的一项研究现在证明了GTP酶发动蛋白在这些事件中的重要作用。