进一步研究人血红蛋白的巯基。
Further studies on the thiol groups of human haemoglobin.
机构信息
Department of Biochemistry, University of Oxford.
出版信息
Biochem J. 1966 Dec;101(3):741-6. doi: 10.1042/bj1010741.
Abstract
When the SH groups of various derivatives of human haemoglobin are converted into their mercuric mercaptides small changes are observed in the optical rotatory dispersion in the range 385-294mmu. These changes are proportionately greater for the reactive than for the unreactive SH groups. These observations have been interpreted in terms of the conformational changes that are likely to occur in the haemoglobin molecule on modification of the SH groups.
摘要
当各种人血红蛋白衍生物的 SH 基团被转化为它们的汞硫醇盐时，在 385-294nm 的旋光色散中观察到微小的变化。对于反应性的 SH 基团，这些变化比非反应性的 SH 基团更大。这些观察结果可以根据 SH 基团修饰时血红蛋白分子可能发生的构象变化来解释。
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本文引用的文献
1
A study of the kinetics of the reaction between thiol compounds and choloracetamide.
Biochem J. 1960 Mar;74(3):577-84. doi: 10.1042/bj0740577.
2
The kinetics of dissociation of the first oxygen molecule from fully saturated oxyhaemoglobin in sheep blood solutions.
Proc R Soc Lond B Biol Sci. 1955 Mar 15;143(912):310-34. doi: 10.1098/rspb.1955.0014.
3
THE DISSOCIATION OF HEMOGLOBIN BY INORGANIC SALTS.
Biochemistry. 1964 Mar;3:291-6. doi: 10.1021/bi00891a002.
4
Some observations on the reactive sulphydryl groups in haemoglobin.
Biochem J. 1962 Aug;84(2):360-4. doi: 10.1042/bj0840360.
5
The reaction of normal adult human haemoglobin with heavy-metal reagents.
Biochem J. 1962 Feb;82(2):247-55. doi: 10.1042/bj0820247.
6
The function of the unreactive thiol groups of normal adult human haemoglobin.
Biochem J. 1962 Feb;82(2):255-62. doi: 10.1042/bj0820255.
7
8
Nature of the unreactive sulphydryl groups in human haemoglobin.
Nature. 1965 Jun 26;206(991):1317-20. doi: 10.1038/2061317a0.
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