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Aerobic incubation of [(14)C]oestradiol, in the presence of surviving gut tissue of the sea urchin Strongylocentrotus franciscanus, or a soluble enzyme system prepared therefrom, resulted in rapid formation of a water-soluble metabolite, identified as oestradiol 3-sulphate. 2. No evidence was obtained for the formation of other metabolic derivatives by the urchin-gut enzymes, or for the presence of the sulphating capacity in any other tissues of the organism under the conditions used. 3. The data are consistent with the possibility that oestradiol, previously detected in the gonads, is synthesized therein and excreted in a conjugated, highly water-soluble form via the gut.

[(14)C]雌二醇在存活的加利福尼亚海胆（Strongylocentrotus franciscanus）肠道组织或从中制备的可溶性酶系统存在下进行有氧孵育，导致迅速形成水溶性代谢物，鉴定为雌二醇 3-硫酸盐。
未在海胆肠道酶中获得其他代谢衍生物的形成证据，也未在所用条件下的任何其他组织中获得硫酸化能力的证据。
这些数据与以下可能性一致：先前在性腺中检测到的雌二醇在其中合成，并通过肠道以共轭的、高度水溶性的形式排泄。

Aerobic incubation of [(14)C]oestradiol, in the presence of surviving gut tissue of the sea urchin Strongylocentrotus franciscanus, or a soluble enzyme system prepared therefrom, resulted in rapid formation of a water-soluble metabolite, identified as oestradiol 3-sulphate. 2. No evidence was obtained for the formation of other metabolic derivatives by the urchin-gut enzymes, or for the presence of the sulphating capacity in any other tissues of the organism under the conditions used. 3. The data are consistent with the possibility that oestradiol, previously detected in the gonads, is synthesized therein and excreted in a conjugated, highly water-soluble form via the gut.

[(14)C]雌二醇在存活的加利福尼亚海胆（Strongylocentrotus franciscanus）肠道组织或从中制备的可溶性酶系统存在下进行有氧孵育，导致迅速形成水溶性代谢物，鉴定为雌二醇 3-硫酸盐。
未在海胆肠道酶中获得其他代谢衍生物的形成证据，也未在所用条件下的任何其他组织中获得硫酸化能力的证据。
这些数据与以下可能性一致：先前在性腺中检测到的雌二醇在其中合成，并通过肠道以共轭的、高度水溶性的形式排泄。

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