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曼谷肠道病毒感染监测。一、从健康儿童粪便标本中分离肠道病毒。

Surveillance of enterovirus infections in Bangkok. I. Isolation of enterovirus from faecal specimens of healthy children.

作者信息

Sangkawibha N, Tuchinda P, Sakuntanaga P, Sunthornsaratul A

出版信息

Southeast Asian J Trop Med Public Health. 1975 Mar;6(1):3-9.

PMID:167453
Abstract

During the period August 1970 through July 1973, about 50 faecal specimens collected each month from healthy pre-school children of lower economic status in Bangkok were studied for virus isolation using primary monkey kidney cells and new born mice. From a total of 1,823 samples, 557 (30.5%) were positive: 86 (4.8%) polioviruses, 77 (4.2%) coxsackieviruses B, 223 (12.2%) echoviruses, and 127 strains (7.0%) of unidentified viruses. Altogether, 45 serotypes of enteric viruses were identified. More than 30 serotypes, including the 3 types of poliovirus, were present each year. Infection rates were higher in males than in females and highest at one year of age, the rates decreasing with progressing age. There was no marked seasonal variation of enterovirus infections in Bangkok. The poliovirus infection index was low from September to January, and the index of polio and non-polio enterovirus infections was highest in April.

摘要

在1970年8月至1973年7月期间,每月从曼谷经济地位较低的健康学龄前儿童中收集约50份粪便标本,使用原代猴肾细胞和新生小鼠进行病毒分离研究。在总共1823份样本中,557份(30.5%)呈阳性:86份(4.8%)为脊髓灰质炎病毒,77份(4.2%)为柯萨奇B组病毒,223份(12.2%)为埃可病毒,127株(7.0%)为未鉴定病毒。总共鉴定出45种肠道病毒血清型。每年存在超过30种血清型,包括3种脊髓灰质炎病毒类型。男性感染率高于女性,一岁时最高,感染率随年龄增长而下降。曼谷肠道病毒感染没有明显的季节性变化。脊髓灰质炎病毒感染指数在9月至1月较低,脊髓灰质炎和非脊髓灰质炎肠道病毒感染指数在4月最高。

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