Vandeursen H, Pittomvils G, Boving R, Baert L
Department of Urology, University Hospital Sint-Pieter, Leuven, Belgium.
J Urol. 1991 Jun;145(6):1146-50. doi: 10.1016/s0022-5347(17)38559-2.
High energy pulsed dye laser lithotripsy (Candela MDL-2000), with energy output upgraded to a maximum of 140 mJ. at the laser fiber tip using the 320 mu core fiber, was compared to the initially commercialized device, with the energy output fixed at 60 mJ. using the 200 mu core fiber (Candela MDL-1). A total of 31 treatments in 28 patients was performed with the Candela MDL-1 device. Complete disintegration or at least fragmentation to spontaneously passable fragments occurred in 18 of 31 cases (58%). Only in 11 of the 24 calcium oxalate monohydrate calculi (46%) was fragmentation achieved. Another 73 laser lithotripsies in 72 patients were performed with the Candela MDL-2000 device. Complete disintegration or at least fragmentation to spontaneously passable fragments was achieved in 67 of 73 treatments (92%). Calcium oxalate monohydrate calculi were successfully treated in 41 of 45 procedures (91%). There was no response to the laser treatment in the only cystine calculus.
高能脉冲染料激光碎石术（坎德拉MDL - 2000），使用320微米芯光纤时，激光光纤尖端的能量输出提升至最高140毫焦，与最初商业化的设备（使用200微米芯光纤，能量输出固定为60毫焦的坎德拉MDL - 1）进行了比较。使用坎德拉MDL - 1设备对28例患者共进行了31次治疗。31例中有18例（58%）实现了完全崩解或至少碎解为可自行排出的碎片。在24例一水草酸钙结石中，只有11例（46%）实现了碎解。使用坎德拉MDL - 2000设备对72例患者进行了另外73次激光碎石术。73次治疗中有67例（92%）实现了完全崩解或至少碎解为可自行排出的碎片。45例手术中有41例（91%）一水草酸钙结石得到成功治疗。唯一的胱氨酸结石对激光治疗无反应。
