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Studies in detoxication: On the alleged formation of p-hydroxylaminobenzenesulphonamide and p-aminophenol from sulphanilamide in vivo, on the colour reactions used for their detection, and on the possible formation of aminophenolsulphonamides.

作者信息

Thorpe W V, Williams R T, Shelswell J

机构信息

The Physiology Department, Medical School, Hospitals Centre, Birmingham.

出版信息

Biochem J. 1941 Jan;35(1-2):52-60. doi: 10.1042/bj0350052.

DOI:10.1042/bj0350052
PMID:16747388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1265469/
Abstract
摘要

相似文献

1
Studies in detoxication: On the alleged formation of p-hydroxylaminobenzenesulphonamide and p-aminophenol from sulphanilamide in vivo, on the colour reactions used for their detection, and on the possible formation of aminophenolsulphonamides.解毒作用的研究：关于体内磺胺类药物据称形成对羟基氨基苯磺酰胺和对氨基酚的情况、用于检测它们的显色反应以及氨基酚磺酰胺的可能形成。
Biochem J. 1941 Jan;35(1-2):52-60. doi: 10.1042/bj0350052.
2
Studies in detoxication: Ethereal sulphate formation in the rabbit after administration of sulphanilamide.解毒研究：给兔子服用磺胺后其体内硫酸酯的形成。
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3
Studies in detoxication: The synthesis of some possible biological oxidation products of sulphanilamide.解毒研究：对氨基苯磺酰胺一些可能的生物氧化产物的合成
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4
The effect of administration of an acetate on detoxication and therapeutic activity of sulphanilamide.给予醋酸盐对磺胺解毒及治疗活性的影响。
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5
The effect of administration of an acetate on the detoxication and therapeutic activity of sulphanilamide. II.醋酸盐给药对磺胺解毒及治疗活性的影响。II.
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6
Structures and rearrangement reactions of 4-aminophenol(H2O)1+ and 3-aminophenol(H2O)1+ clusters.4-氨基苯酚(H2O)1+和3-氨基苯酚(H2O)1+团簇的结构与重排反应
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Visual and colorimetric detection of p-aminophenol in environmental water and human urine samples based on anisotropic growth of Ag nanoshells on Au nanorods.基于金纳米棒上银纳米壳的各向异性生长对环境水样和人体尿液样本中的对氨基酚进行视觉和比色检测。
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Potential for natural and enhanced attenuation of sulphanilamide in a contaminated chalk aquifer.受污染白垩含水层中磺胺的自然衰减和强化衰减潜力
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Photo-oxidation of sulphanilamide to blue product.磺胺的光氧化生成蓝色产物。
Pak J Pharm Sci. 1989 Jul;2(2):13-7.
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Effects of lipoic acid and dihydrolipoic acid on 4-aminophenol-mediated erythrocytic toxicity in vitro.硫辛酸和二氢硫辛酸对4-氨基苯酚介导的体外红细胞毒性的影响。
Basic Clin Pharmacol Toxicol. 2006 Sep;99(3):225-9. doi: 10.1111/j.1742-7843.2006.pto_499.x.

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The fate of certain organic acids and amides in the rabbit: 2. p-Hydroxybenzoic acid and its amide.家兔体内某些有机酸和酰胺的代谢命运：2. 对羟基苯甲酸及其酰胺
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The metabolism of sulphapyridine in the rabbit.磺胺吡啶在兔体内的代谢
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The metabolism of sulphonamides: 2. The isolation and identification of 3-hydroxysulphanilamide as the oxidation product of sulphanilamide in the rabbit.磺胺类药物的代谢：2. 3-羟基磺胺的分离与鉴定，其为兔体内磺胺的氧化产物
Biochem J. 1946;40(2):219-22. doi: 10.1042/bj0400219.
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Studies in detoxication: The identification of catechol-4-sulphonamide as a metabolic product of p-hydroxybenzenesulphonamide in the rabbit. The synthesis of derivatives of catecholsulphonamide.解毒研究：鉴定儿茶酚-4-磺酰胺为对羟基苯磺酰胺在兔体内的代谢产物。儿茶酚磺酰胺衍生物的合成。
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The metabolism of aminophenols, oformamidophenol, benzoxazole, 2-methyl- and 2-phenyl-benzoxazoles and benzoxazolone in the rabbit.对氨基苯酚、甲酰氨基苯酚、苯并恶唑、2-甲基苯并恶唑、2-苯基苯并恶唑及苯并恶唑酮在兔体内的代谢情况
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The metabolism of sulphamezathine, 4:6-dimethylpyrimidine and 2-amino-4:6-dimethylpyrimidine in the rabbit with observations on the hydroxylation of some other sulphonamides.磺胺甲嘧啶、4:6-二甲基嘧啶和2-氨基-4:6-二甲基嘧啶在兔体内的代谢以及对其他一些磺胺类药物羟基化作用的观察
Biochem J. 1951 Apr;48(4):400-6. doi: 10.1042/bj0480400.
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THE ISOLATION OF P-CHLORONITROSOBENZENE FROM THE BLOOD OF DOGS INJECTED WITH P-CHLOROANILINE.从注射对氯苯胺的狗的血液中分离对氯亚硝基苯。
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1963 Nov 8;246:163-74. doi: 10.1007/BF00245002.
9
The metabolism of 2:3-, 2:6- and 3:5-dichloronitrobenzene and the formation of a mercapturic acid from 2:3:4:5-tetrachloronitro-benzene in the rabbit.兔体内2:3-、2:6-和3:5-二氯硝基苯的代谢以及2:3:4:5-四氯硝基苯形成巯基尿酸的过程
Biochem J. 1957 Dec;67(4):607-16. doi: 10.1042/bj0670607.
10
The metabolism of the trichloronitrobenzenes in the rabbit.家兔体内三氯硝基苯的代谢
Biochem J. 1957 Aug;66(4):610-21. doi: 10.1042/bj0660610.

本文引用的文献

1
ON THE URINARY EXCRETION OF "FREE" SULFAPYRIDINE.论“游离”磺胺吡啶的尿排泄
Science. 1940 May 17;91(2368):486. doi: 10.1126/science.91.2368.486.
2
Studies in detoxication: The synthesis of some possible biological oxidation products of sulphanilamide.解毒研究：对氨基苯磺酰胺一些可能的生物氧化产物的合成
Biochem J. 1941 Jan;35(1-2):61-5. doi: 10.1042/bj0350061.
3
Studies in detoxication: Ethereal sulphate formation in the rabbit after administration of sulphanilamide.解毒研究：给兔子服用磺胺后其体内硫酸酯的形成。
Biochem J. 1940 Apr;34(4):528-31. doi: 10.1042/bj0340528.
4
The effect of administration of an acetate on detoxication and therapeutic activity of sulphanilamide.给予醋酸盐对磺胺解毒及治疗活性的影响。
Biochem J. 1939 Oct;33(10):1688-93. doi: 10.1042/bj0331688.
5
Porphyrinuric action of drugs related to sulphanilamide. Comparison with reported toxicity, therapeutic efficiency and causation of methaemoglobinaemia. Definition of the structure responsible for porphyrinuric action.与磺胺类药物相关的药物的卟啉尿作用。与已报道的毒性、治疗效果及高铁血红蛋白血症病因的比较。对卟啉尿作用相关结构的定义。
Biochem J. 1939 Jun;33(6):960-77. doi: 10.1042/bj0330960.
6
The role of the aromatic amino group in deranged pigment metabolism.芳香氨基在色素代谢紊乱中的作用。
Biochem J. 1939 May;33(5):697-708. doi: 10.1042/bj0330697.
7
The quantitative extraction of histamine from tissues by electrodialysis.通过电渗析从组织中定量提取组胺。
Biochem J. 1933;27(5):1394-9. doi: 10.1042/bj0271394.