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Studies in detoxication. 31. The isolation of m- and p-cyanophenols as metabolites of cyanobenzene (benzonitrile) and the problem of the orientation of hydroxyl groups formed in vivo.

作者信息

Smith J N, Williams R T

机构信息

Department of Biochemistry, St Mary's Hospital Medical School, London, W. 2.

出版信息

Biochem J. 1950 Feb;46(2):243-8. doi: 10.1042/bj0460243.

DOI:10.1042/bj0460243
PMID:16748668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1275119/
Abstract
摘要

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Metabolism of the herbicide 2,6-dichlorobenzonitrile in rabbits and rats.除草剂 2,6-二氯苯甲腈在兔和大鼠体内的代谢。
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Studies in detoxication. 40. The metabolism of nitrobenzene in the rabbit; o-, m- and p-nitrophenols, o-, m- and p-aminophenols and 4-nitrocatechol as metabolites of nitrobenzene.解毒研究。40. 家兔体内硝基苯的代谢；邻、间、对硝基苯酚，邻、间、对氨基酚以及4-硝基邻苯二酚作为硝基苯的代谢产物
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Studies in detoxication. 39. Nitro compounds; (a) the metabolism of o-, m- and p-nitrophenols in the rabbit; (b) the glucuronides of the mononitrophenols and observations on the anomalous optical rotations of triacetyl beta-o-nitrophenyl glucuronide and its methyl ester.解毒作用的研究。39. 硝基化合物；(a) 兔体内邻、间、对硝基苯酚的代谢；(b) 单硝基苯酚的葡糖醛酸苷以及对三乙酰基-β-邻硝基苯基葡糖醛酸苷及其甲酯异常旋光性的观察。
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Studies in detoxication. 51. The determination of catechols in urine, and the formation of catechols in rabbits receiving halogenobenzenes and other compounds; dihydroxylation in vivo.解毒研究。51. 尿液中儿茶酚的测定，以及接受卤代苯和其他化合物的兔子体内儿茶酚的形成；体内二羟基化作用。
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Studies on the mechanism of acute toxicity of nitriles in mice.
Arch Toxicol. 1984 Mar;55(1):47-54. doi: 10.1007/BF00316585.
10
The comparative metabolism of 2,6-dichlorothiobenzamide (Prefix) and 2,6-dichlorobenzonitrile in the dog and rat.2,6-二氯硫代苯甲酰胺（前缀）与2,6-二氯苯腈在犬类和大鼠体内的代谢比较
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本文引用的文献

1
The metabolism of chrysene: the isolation of 3-methoxychrysene by methylation of the phenolic metabolite of chrysene from rat faeces.屈的代谢：通过对大鼠粪便中屈的酚类代谢物进行甲基化反应分离得到3-甲氧基屈。
Biochem J. 1949;44(5):604-6. doi: 10.1042/bj0440604.
2
Studies in detoxication. 22. The metabolism of phenacetin (p-ethoxyacetanilide) in the rabbit and a further observation on acetanilide metabolism.解毒研究。22. 非那西丁（对乙氧基乙酰苯胺）在兔体内的代谢以及对乙酰苯胺代谢的进一步观察。
Biochem J. 1949;44(2):239-42.
3
The fate of certain organic acids and amides in the rabbit. 5. o- and m-hydroxybenzoic acids and amides.家兔体内某些有机酸和酰胺的代谢 fate。5. 邻羟基苯甲酸和间羟基苯甲酸及其酰胺
Biochem J. 1948;43(4):561-7. doi: 10.1042/bj0430561.
4
Studies in detoxication. 18. A study of the relation between conjugation and deamination of p-hydroxybenzylamine and related compounds in the rabbit.解毒作用的研究。18. 家兔对羟基苄胺及相关化合物的结合与脱氨基作用之间关系的研究。
Biochem J. 1948;43(2):296-303.
5
Studies in detoxication: 16. The metabolism of acetanilide in the rabbit.解毒研究：16. 乙酰苯胺在兔体内的代谢
Biochem J. 1948;42(4):538-44. doi: 10.1042/bj0420538.
6
The metabolic conversion of naphthalene to 1:2-dihydronaphthalene-1:2-diol.萘向1,2 - 二氢萘 - 1,2 - 二醇的代谢转化。
Biochem J. 1947;41(3):417-22. doi: 10.1042/bj0410417.
7
Oxidation of phenol and benzoic acid by some soil bacteria.某些土壤细菌对苯酚和苯甲酸的氧化作用。
Biochem J. 1947;41(3):373-82. doi: 10.1042/bj0410373.
8
The metabolism of sulphonamides: 3. The detection of 3-hydroxysulphanilamide in the urine of hospital patients treated with sulphanilamide.磺胺类药物的代谢：3. 对接受磺胺治疗的住院患者尿液中3-羟基磺胺的检测。
Biochem J. 1947;41(1):1-8. doi: 10.1042/bj0410001.
9
The fate of certain organic acids and amides in the rabbit: 1. Benzoic and phenylacetic acids and their amides.家兔体内某些有机酸和酰胺的代谢情况：1. 苯甲酸、苯乙酸及其酰胺。
Biochem J. 1946;40(1):134-9.
10
Studies in detoxication: The influence of (a) dose and (b) o-, m- and p-substitution on the sulphate detoxication of phenol in the rabbit.解毒作用的研究：（a）剂量以及（b）邻位、间位和对位取代对兔体内苯酚硫酸盐解毒作用的影响。
Biochem J. 1938 May;32(5):878-87. doi: 10.1042/bj0320878.