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[主动脉缩窄的外科治疗。墨西哥国家心脏病学研究所的长期结果]

[Sugical treatment of aortic coarctation. Long-term results at National Institute of Cardiology of Mexico].

作者信息

Cervantes Salazar Jorge Luis, Ramírez Marroquín Samuel, Benita Bordes Antonio, Rosas Peralta Martín, Attie Fause

机构信息

Servicio de Cirugía de Cardiopatías Congénitas, Departamento de Cirugía, Institute Nacional de Cardiología "Ignacio Chávez" (INCICH, Juan Badiano Num. 1, Col. Sección XVI, Tlalpan 14080, México, DF.

出版信息

Arch Cardiol Mex. 2006 Jan-Mar;76(1):63-8.

Abstract

OBJECTIVES

Evaluate long-term evolution of patients submitted to surgery for coarctation of the aorta. Compare event free survival in younger vs older patients at the time of surgical correction.

METHODS

We reviewed the clinical records of patients operated for coarctation of the aorta from January 1 1980 to December 31 1994. The mean follow-up ranged from 9 to 23 years (mean 10.9 y). Final events registered were recoarctation, death, systemic hypertension, endocarditis, stroke, aneurisms.

RESULTS

Two hundred and sixteen patients were found with mean age 13 +/- 12 y male gender was most frequent (61%). Recoarctation was found in 13 patients (6.02%), persistent hypertension in 14.1%. Event free survival at 10 years was 86.2%. In patients less than 10 y was 89% vs 80.2% in older patients. Hypertension free survival in patients less than 10 y was 98.3% vs 80.1% in older patients (p < 0.001).

CONCLUSIONS

Our data confirms that surgical treatment for coarctation of the aorta is associated with low morbidity and mortality at long-term with reduced rate of recoarctation (7%). Early correction (< 10 y) is associated with a better long term survival. Hypertension and use of pharmacologic treatment are reduced after surgery and persist in the long-term evolution.

摘要

目的

评估接受主动脉缩窄手术患者的长期病情演变。比较手术矫正时年轻患者与老年患者的无事件生存率。

方法

我们回顾了1980年1月1日至1994年12月31日接受主动脉缩窄手术患者的临床记录。平均随访时间为9至23年(平均10.9年)。记录的最终事件包括再缩窄、死亡、系统性高血压、心内膜炎、中风、动脉瘤。

结果

共发现216例患者,平均年龄13±12岁,男性居多(61%)。13例患者(6.02%)出现再缩窄,14.1%出现持续性高血压。10年时的无事件生存率为86.2%。10岁以下患者为89%,老年患者为80.2%。10岁以下患者的无高血压生存率为98.3%,老年患者为80.1%(p<0.001)。

结论

我们的数据证实,主动脉缩窄的手术治疗长期来看发病率和死亡率较低,再缩窄率降低(7%)。早期矫正(<10岁)与更好的长期生存率相关。手术后高血压及药物治疗的使用减少,但在长期病情演变中仍持续存在。

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