Beifuss B, Borelli C, Korting H C
Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig-Maximilians-Universität, Frauenlobstrasse 9-11, 80337, München.
Hautarzt. 2006 Jun;57(6):487-8, 490-2. doi: 10.1007/s00105-006-1156-1.
The clinical presentation of fungal infections of the skin, hair, or nails may be varied and confusing. To avoid delays in treatment and early spread of the infection, adequate diagnostics are necessary. This requires both the clinical expertise of the physicians as well as the capability to perform various laboratory tests. Classical methods are based on microscopy, different culture procedures, and histological examination. Genotypic approaches for the detection and identification of fungal pathogens have improved the speed and accuracy of laboratory diagnosis in the last few years, although further evaluation using molecular biology-based methods should be routinely applied in practice.
皮肤、毛发或指甲真菌感染的临床表现可能多种多样且令人困惑。为避免治疗延误和感染早期扩散,进行充分的诊断很有必要。这既需要医生的临床专业知识,也需要进行各种实验室检测的能力。传统方法基于显微镜检查、不同的培养程序和组织学检查。在过去几年中,用于检测和鉴定真菌病原体的基因分型方法提高了实验室诊断的速度和准确性,尽管基于分子生物学的方法的进一步评估应在实践中常规应用。