Sinenchenko G I, Selivanov E A, Musinov I M
Vestn Khir Im I I Grek. 2006;165(2):15-9.
In patients with gastrointestinal bleedings there occurs activation of the hemostasis system directed to arrest of bleeding. Short-term hypercoagulation directed to arrest of the bleeding gives place to hypocoagulative changes. Their degree and duration depend on the severity and rate of blood loss. The excessive intravascular activation of blood is accompanied by the formation of fibrin deposits not only in the area of the bleeding source but in other regions of the blood channel. There appears disseminated intravascular coagulation of blood deteriorating the reparative processes in the ulcer, initiating and maintaining generalized plasminemia which promotes the thrombus lysis in the ulcer crater and recurrent bleeding.
在胃肠道出血患者中，会发生旨在止血的止血系统激活。旨在止血的短期高凝状态会被低凝状态改变所取代。其程度和持续时间取决于失血的严重程度和速度。血液在血管内的过度激活不仅会在出血源部位形成纤维蛋白沉积物，还会在血管通道的其他区域形成。出现弥散性血管内凝血，这会使溃疡的修复过程恶化，引发并维持全身性纤溶血症，促进溃疡 crater 内血栓溶解和再次出血。 （注：原文中“crater”可能有误，推测可能是“cavity”，翻译为“腔”“空洞”等更合适，但按要求未修改直接翻译）
