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伊巴丹大学学院医院结核病的临床表现模式以及结核病与艾滋病毒合并感染的医院患病率:五年(1998 - 2002年)回顾

Pattern of presentation of tuberculosis and the hospital prevalence of tuberculosis and HIVco-infection in University College Hospital, Ibadan: a review of five years (1998 - 2002).

作者信息

Ige O M, Sogaolu O M, Ogunlade O A

机构信息

Pulmonary Unit, Department of Medicine, University College Hospital, Ibadan, Nigeria.

出版信息

Afr J Med Med Sci. 2005 Dec;34(4):329-33.

PMID:16752660
Abstract

A 5-year review (1998-2002) was done at the pulmonary unit of the University College Hospital (UCH), Ibadan, Nigeria to determine the pattern of presentation of tuberculosis (TB) and the prevalence of TB and human Immunodefiency virus (HIV) co-infection. A total of one thousand patients were managed for TB but 777 confirmed as having TB had their case files analysed. There were 418 males and 359 females giving a male to female ratio of 1.16:1.00. Pulmonary tuberculosis (PTB) accounted for 78.6% of the patients seen over the period, followed by tuberculosis meningitis 7.8% then TB spine 6.8% and that of the lymph node 4.1%. The other types of TB (Abdomen, pericardial and miliary) accounted for less than 3%. The highest number of cases of tuberculosis (27.8%) was in the 20-29 age group for both male and female followed by those less than 40 years (26.0%). Less than 20% (18.3%) were 40 years old and above. The number of TB cases decreased sharply from a total of 188 in the year 2000 to 89 in 2002. The decrease in number was most likely due to the fact that directly observed therapy short course (DOTS) are now available at other centres within the city and its environs. Only 180 out of the 640 cases of TB were confirmed as HIV positive giving a seroprevalence rate of 28.12%. The annual distribution of TB/HIV co-infection showed a rising trend from 26 cases in 1998 to 42 cases in 2002.

摘要

在尼日利亚伊巴丹大学学院医院(UCH)的肺病科进行了一项为期5年(1998 - 2002年)的回顾性研究,以确定结核病(TB)的临床表现模式以及结核病与人类免疫缺陷病毒(HIV)合并感染的患病率。共有1000例患者接受了结核病治疗,但对777例确诊为结核病的患者的病历进行了分析。其中男性418例,女性359例,男女比例为1.16:1.00。在此期间,肺结核(PTB)占所诊治患者的78.6%,其次是结核性脑膜炎占7.8%,脊柱结核占6.8%,淋巴结结核占4.1%。其他类型的结核病(腹部、心包和粟粒性)占比不到3%。结核病病例数最多的是20 - 29岁年龄组,男性和女性均占27.8%,其次是40岁以下的人群(占26.0%)。40岁及以上的患者不到20%(占18.3%)。结核病病例数从2000年的188例急剧下降至2002年的89例。病例数下降很可能是因为该市及其周边其他中心现在也提供直接观察下的短程治疗(DOTS)。在640例结核病病例中,只有180例被确诊为HIV阳性,血清阳性率为28.12%。结核病/HIV合并感染的年度分布呈上升趋势,从1998年的26例增至2002年的42例。

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