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[胰十二指肠切除术后胰空肠吻合与胰胃吻合的比较]

[Pancreatico-jejunal vs pancreatico-gastric anastomosis after cephalic duodenopancreatectomy].

作者信息

Miron A, Ardelean M, Sîrbu-Boeţi V, Calu V, Giulea C, Pop A I

机构信息

Departamentul de Chirurgie Generală al Spitalului Elias, Bucureşti.

出版信息

Chirurgia (Bucur). 2006 Mar-Apr;101(2):151-7.

Abstract

Pancreatoduodenectomy has been for a long time a procedure with high postoperative morbidity and mortality. Several complications after pancreatic resections are known, but one of the most severe is the fistula of the pancreatic anastomosis. Avoiding the pancreatic fistula caused many surgical innovations regarding the procedure of reestablishing the continuity after pancreatoduodenectomy. The aim of this retrospective study was to compare pancreatico-jejunostomy vs pancreatico-gastrostomy with regard to safety of pancreatic anastomosis after pancreatoduodenectomy. No technique was proved to be superior so far, the benefits of these 2 types of pancreatic anastomosis being the subject for intense debates. From 2000 to 2004, 17 patients underwent pancreatoduodenectomy, for pancreas, ampulla, distal bile duct or duodenum cancers. Pancreatic anastomosis was accomplished by pancreatico-gastrostomy in 11 cases and by pancreatico-jejunostomy in 6 cases. There was no significant difference between the two groups (age, gender and primary disease). Comparison between the two groups was made mainly analysing postoperative mortality and morbidity. Postoperative morbidity was 9,1% after pancreatico-gastrostomy and 33,3% after pancreatico-jejunostomy. Postoperative mortality was none after pancreatico-gastrostomy and 16,7% after pancreatico-jejunostomy. This study seems to demonstrate the superiority of the pancreatico-gastric anastomosis, but in most cases the surgeon will choose based on his experience. These results have to be confirmed or invalidated by a prospective multicentric randomised study.

摘要

长期以来,胰十二指肠切除术一直是一种术后发病率和死亡率较高的手术。胰腺切除术后的几种并发症是已知的,但最严重的并发症之一是胰肠吻合口瘘。为避免胰瘘,在胰十二指肠切除术后重建连续性的手术方法上出现了许多创新。这项回顾性研究的目的是比较胰十二指肠切除术后胰胃吻合术和胰肠吻合术在胰肠吻合安全性方面的差异。到目前为止,尚无技术被证明更具优势,这两种胰肠吻合术的益处一直是激烈争论的主题。2000年至2004年,17例患者因胰腺、壶腹、远端胆管或十二指肠癌接受了胰十二指肠切除术。11例患者采用胰胃吻合术完成胰肠吻合,6例患者采用胰肠吻合术。两组之间(年龄、性别和原发性疾病)无显著差异。主要通过分析术后死亡率和发病率对两组进行比较。胰胃吻合术后的术后发病率为9.1%,胰肠吻合术后为33.3%。胰胃吻合术后无术后死亡病例,胰肠吻合术后为16.7%。这项研究似乎证明了胰胃吻合术的优越性,但在大多数情况下,外科医生会根据自己的经验进行选择。这些结果必须通过前瞻性多中心随机研究来证实或否定。

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