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胰十二指肠切除术后胰管空肠吻合术与胰管胃吻合术的比较研究结果

Pancreaticojejunostomy vs. pancreaticogastrostomy following pancreaticoduodenectomy: results of comparative study.

作者信息

Makni A, Bedioui H, Jouini M, Chebbi F, Ksantini R, Fetirich F, Rebai W, Daghfous A, Ayedi S, Kacem M, Ben Safta Z

机构信息

Department of Digestive Surgery 'A', La Rabta Hospital University, Tunis, Tunisia.

出版信息

Minerva Chir. 2011 Aug;66(4):295-302.

Abstract

AIM

Several techniques have been proposed for reconstructing pancreatico-digestive continuity, which the first goal is reducing the rate of pancreatic leakage after pancreaticoduodenectomy. Only a limited number studies have been carried out. Our objective is to compare the results of pancreaticojejunostomy versus pancreaticogastrostomy following pancreaticoduodenectomy.

METHODS

This is a retrospective and comparative study about 80 patients who underwent pancreaticoduodenectomy. These patients were divided into two groups: pancreaticojejunostomy (group PJ) and pancreaticogastrostomy (group PG).

RESULTS

The PJ group included 39 patients, while 41 patients were included in the PG group. There were no differences between the two groups concerning: patients' demographics, risk factors, indication, mean duration of surgery, texture of pancreatic tissue, need for intraoperative blood transfusion and postoperative prophylactic octreotide. Overall, the mortality postoperative rate was 7.5% (N.=6), the incidence of surgical complications was 50% (51.3% in PJ, 48.8% in PG; P=0.823, not significant). Pancreatic fistula was the most frequent complication, occurring in 17.5% of patients (25.6% in PJ and 9.8% in PG; P=0.062, almost significant). 7.7% of patients who underwent PJ and 14.6% of patients who underwent PG required a second surgical intervention (P=0.326, not significant). There were no differences between the two groups PG and PJ concerning: Postoperative hemorrhage (P=0.63), biliary fistula (P=0.09), acute pancreatitis (P=0.95), delayed gastric emptying (P=0.33). The mean postoperative hospitalisation period stay was similar in both groups (P=0.63)

CONCLUSION

There were not any significant differences between the two groups in the overall postoperative complication rate, the incidence of postoperative haemorrhage, biliary fistula, acute pancreatitis, and delayed.

摘要

目的

已提出多种重建胰消化道连续性的技术,其首要目标是降低胰十二指肠切除术后胰漏发生率。但仅有有限数量的研究。我们的目的是比较胰十二指肠切除术后胰空肠吻合术与胰胃吻合术的结果。

方法

这是一项对80例行胰十二指肠切除术患者的回顾性比较研究。这些患者被分为两组:胰空肠吻合术组(PJ组)和胰胃吻合术组(PG组)。

结果

PJ组包括39例患者,PG组包括41例患者。两组在以下方面无差异:患者人口统计学特征、危险因素、适应证、平均手术时长、胰腺组织质地、术中输血需求及术后预防性使用奥曲肽。总体而言,术后死亡率为7.5%(n = 6),手术并发症发生率为50%(PJ组为51.3%,PG组为48.8%;P = 0.823,无显著差异)。胰瘘是最常见的并发症,发生在17.5%的患者中(PJ组为25.6%,PG组为9.8%;P = 0.062,接近显著差异)。接受PJ手术的患者中有7.7%,接受PG手术的患者中有14.6%需要二次手术干预(P = 0.326,无显著差异)。PG组和PJ组在以下方面无差异:术后出血(P = 0.63)、胆瘘(P = 0.09)、急性胰腺炎(P = 0.95)、胃排空延迟(P = 0.33)。两组术后平均住院时间相似(P = 0.63)

结论

两组在总体术后并发症发生率、术后出血、胆瘘、急性胰腺炎及延迟发生率方面无显著差异。

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