Peterová V, Forejtová S, Pavelka K
Department of Radiodiagnostics of the First Faculty of Medicine, Charles University in Prague, Czech Republic.
Prague Med Rep. 2006;107(1):26-36.
Results of the spinal magnetic resonance (MR) in patients with ankylosing spondylitis (AS) were evaluated prospectively in correlation with age, symptoms duration and some inflammatory tests. 20 patients with AS were prospectively examined by complex clinical and laboratory tests. All were examined with X-ray and 1,5T magnetic resonance. The visibility, margination and extent of acute and chronic pathological vertebral lesions were qualitatively and quantitatively compared statistically. The axial form of AS strongly prevailed (70%). If acute AS vertebral changes are evaluated CRP did not correlated with local vertebral changes, erythrocyte sedimentation rate and functional tests BASDAI and BASFI correlated with vertebral changes on the various significance level due to the MR sequence used. Chronic spinal changes correlated with age of the patients and duration of the symptoms. BASFI test with chronic changes did not correlate. MR is the best method for evaluating changes in vertebrae and in the adjacent soft tissues. The excellent evaluation of acute and chronic local MR changes of vertebral marrow is provided by Braun's scoring system. In acute AS changes short T1 inversion recovery (STIR) sequence showed most vertebral marrow changes, while in the chronic AS changes T1 weighted images were the statistically significantly best sequence in depicting the marrow and ligamentous pathology.
对强直性脊柱炎（AS）患者的脊柱磁共振成像（MR）结果进行了前瞻性评估，并与年龄、症状持续时间及一些炎症检测结果相关联。对20例AS患者进行了全面的临床和实验室检查。所有患者均接受了X线和1.5T磁共振成像检查。对急性和慢性病理性椎体病变的可见性、边界及范围进行了定性和定量比较，并进行统计学分析。AS的轴向型占主导（70%）。评估急性AS椎体改变时，CRP与局部椎体改变无相关性，红细胞沉降率及功能测试BASDAI和BASFI因所使用的MR序列不同，在不同显著水平上与椎体改变相关。慢性脊柱改变与患者年龄及症状持续时间相关。BASFI测试与慢性改变无相关性。MR是评估椎体及相邻软组织改变的最佳方法。Braun评分系统能很好地评估椎体骨髓的急性和慢性局部MR改变。在急性AS改变中，短T1反转恢复（STIR）序列显示的椎体骨髓改变最多，而在慢性AS改变中，T1加权图像在显示骨髓和韧带病变方面在统计学上是显著最佳序列。
