Lénárt Péter, Peters Jan-Michael
Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.
Curr Biol. 2006 Jun 6;16(11):R412-4. doi: 10.1016/j.cub.2006.05.008.
The Mad2 protein is required to delay sister chromatid separation until all chromosomes have been aligned on the mitotic spindle. Two recent studies provide new insights into how Mad2 contributes to this remarkable task.
Mad2蛋白是使姐妹染色单体分离延迟至所有染色体在有丝分裂纺锤体上排列整齐所必需的。最近的两项研究为Mad2如何完成这一非凡任务提供了新的见解。