Brumsen C, de Man R A, van der Maas A P, Swart G R
Westeinde Ziekenhuis, afd. Interne Geneeskunde, 's-Gravenhage.
Ned Tijdschr Geneeskd. 1991 Apr 27;135(17):763-6.
A 39-year-old man, known as a heavy drinker, presented with general malaise, abdominal pain, a history of icterus and progressive weight loss. He was found to have an acute hepatitis B infection and pancreatitis with pancreatic pseudocysts. A diagnosis of polyarteritis nodosa was made on clinical grounds, and confirmed pathologically. The patient was treated with high-dose corticosteroids, cyclophosphamide, antibiotics and drainage. However, the disease was progressive and the patient died. Pancreatitis in relation to polyarteritis nodosa, the association with hepatitis B infection, and new therapeutic possibilities are discussed.
一名39岁男性,有酗酒史,出现全身不适、腹痛、黄疸史及进行性体重减轻。他被发现患有急性乙型肝炎感染和伴有胰腺假性囊肿的胰腺炎。基于临床症状诊断为结节性多动脉炎,并经病理证实。患者接受了大剂量皮质类固醇、环磷酰胺、抗生素治疗及引流。然而,疾病仍在进展,患者最终死亡。本文讨论了与结节性多动脉炎相关的胰腺炎、与乙型肝炎感染的关联以及新的治疗可能性。