Deng Wang-Dong, Jiang Xue-Wu
Department of Urology, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
Zhonghua Nan Ke Xue. 2006 May;12(5):446-9.
The testicular gubernaculum plays an important role in testicular descent and development. Its differentiation and development are affected by many factors. Androgens, calcitonin gene-related peptide (CGRP), insulin-like factor 3 (INSL3), Müllerian inhibiting substance (MIS), epidermal growth factor (EGF) and environmental estrogens (EEs) are involved in gubernacular development. The effect of CGRP, INSL3 and especially EEs on genital system has been attracted more attention.
睾丸引带在睾丸下降和发育过程中发挥着重要作用。其分化和发育受多种因素影响。雄激素、降钙素基因相关肽（CGRP）、胰岛素样因子3（INSL3）、苗勒管抑制物质（MIS）、表皮生长因子（EGF）以及环境雌激素（EEs）均参与引带发育。CGRP、INSL3尤其是EEs对生殖系统的影响已受到更多关注。
