北非的巨幼细胞贫血

Megaloblastic anemia in North Africa.

作者信息

Maktouf Chokri, Bchir Attouma, Louzir Hechmi, Mdhaffer Moez, Elloumi Moez, Ben Abid Hela, Meddeb Balkis, Makni Faiza, Laatiri Adnene, Soussi Taoufik, Hafsia Aicha, Dellagi Koussay

出版信息

Haematologica. 2006 Jul;91(7):990-1. Epub 2006 Jun 1.

PMID:16757418

Abstract

We prospectively studied 478 patients with megaloblastic anemia living in Tunisia. Overall, 98% of patients had vitamin B12 deficiency. Pernicious anemia accounted for most of these cases, and median age at presentation was 45 years. Megaloblastic anemia occurred in 19 subjects under 15 years of age, and of these, nine had the Immerslund-Graesbeck syndrome.

摘要

我们对突尼斯的478例巨幼细胞贫血患者进行了前瞻性研究。总体而言，98%的患者存在维生素B12缺乏。恶性贫血占这些病例的大多数，就诊时的中位年龄为45岁。19名15岁以下的受试者发生了巨幼细胞贫血，其中9人患有伊默斯伦德-格雷斯贝克综合征。