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大鼠主嗅球中钙视网膜蛋白免疫反应性球周细胞的年龄相关变化。

Age-related changes in calretinin-immunoreactive periglomerular cells in the rat main olfactory bulb.

作者信息

Hwang In Koo, Yoo Ki-Yeon, Nam Young Sam, Choi Jung Hoon, Seo Kangmoon, Lee In Se, Jung Ju Young, Kang Tae-Cheon, Oh Yang-Seok, Won Moo Ho

机构信息

Department of Anatomy, College of Medicine, Hallym University, Chunchon, South Korea.

出版信息

J Vet Med Sci. 2006 May;68(5):465-9. doi: 10.1292/jvms.68.465.

DOI:10.1292/jvms.68.465
PMID:16757889
Abstract

The changes of calretinin (CR)-immunoreactive periglomerular cells in the glomerular layer of the main olfactory bulb (MOB) were investigated in rats differing ages from postnatal month 1 (PM 1) to PM 24. The number of cresyl violet-positive periglomerular cells was similar between PM 1 and PM 12, but they decreased slightly in the PM 24 group. The size of CR-immunoreactive periglomerular cells in the glomerular layer increased with age, while their numbers did not change significantly in the PM 6-PM 24 groups. In the PM 24 group, numbers of CR-positive periglomerular cell bodies and their processes decreased, while the size of CR-positive cell bodies in the glomeruli was larger than that of the previous groups. These results suggest that CR-immunoreactive periglomerular cells in the rat MOB are well-developed in the PM 6 group, and that periglomerular cells in the PM 24 group show poor CR-immunoreactivity compared to those in the PM 6 group.

摘要

研究了出生后1个月(PM 1)至24个月大的大鼠主嗅球(MOB)肾小球层中钙视网膜蛋白(CR)免疫反应性球周细胞的变化。PM 1组和PM 12组间甲酚紫阳性球周细胞数量相似,但在PM 24组中略有减少。肾小球层中CR免疫反应性球周细胞的大小随年龄增加,而在PM 6 - PM 24组中其数量无显著变化。在PM 24组中,CR阳性球周细胞体及其突起数量减少,而肾小球中CR阳性细胞体的大小大于先前各组。这些结果表明,大鼠MOB中CR免疫反应性球周细胞在PM 6组发育良好,且与PM 6组相比,PM 24组的球周细胞表现出较差的CR免疫反应性。

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